Plummeting blood sugar can accelerate eye damage due to diabetes. Results in mice suggest that a new drug targeting hypoxia inducible factor could help.
In diabetic macular edema, senescent cells build up in the retina, leading to vision loss. A new drug forces these undead cells to die, healing the retina.
James Fujimoto, Eric Swanson, and David Huang developed optical coherence tomography, which transformed ophthalmological practice and spurred new imaging applications.
As global regulations shift toward animal-free testing, how can researchers develop more biologically relevant in vitro models to advance drug discovery?