CRISPR

Previous genome editing techniques only work when delivered early in life. This approach could help preserve hearing that is lost later on. 

Natural killer cells can sometimes attack beneficial CAR T cell immunotherapies. Now, researchers have discovered why and a potential way to stop them.

A new method called “REVeRT” expands the capabilities of gene delivery platforms by transporting larger genes than previously possible.  

CRISPR-edited immune cells may help patients with T-cell leukemia, albeit with immunotherapy-related risks.

Negative childhood experiences can leave epigenetic scars that haunt organisms for life.

For decades, treatment options for sickle cell disease have been extremely limited. Soon, gene therapies and a host of pharmaceuticals could alleviate the immense burden of this disease.

Mireille Kamariza develops new chemistry-driven diagnostics for tuberculosis that can reduce the time to treatment from weeks to minutes.

Currently, the only cure for alpha thalassemia is a bone marrow transplant, but the success of gene therapies for related conditions points to a potential new cure.

Genome-wide CRISPR screens in living organisms reveal mechanisms that cell culture studies overlook.

George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.