CRISPR

Advances in microfluidics are enabling more powerful, high throughput applications in single cell and therapeutic discovery.

ArsenalBio equips T cells with multiple weapons to identify, attack, and persist against tumors, bringing the power of CAR T cell technology to solid cancers.

Virus-inspired delivery methods enable gene editing of dysregulated microbes.

An enzyme reconstructed from a three-billion-year-old bacterium widens gene editing capabilities to even more regions of the genome.

Previous genome editing techniques only work when delivered early in life. This approach could help preserve hearing that is lost later on. 

Natural killer cells can sometimes attack beneficial CAR T cell immunotherapies. Now, researchers have discovered why and a potential way to stop them.

A new method called “REVeRT” expands the capabilities of gene delivery platforms by transporting larger genes than previously possible.  

CRISPR-edited immune cells may help patients with T-cell leukemia, albeit with immunotherapy-related risks.

Negative childhood experiences can leave epigenetic scars that haunt organisms for life.

For decades, treatment options for sickle cell disease have been extremely limited. Soon, gene therapies and a host of pharmaceuticals could alleviate the immense burden of this disease.