cellular metabolism

Preclinical data show a first-in-class transdermal bicarbonate therapy increases tumor pH, reactivates T cells and slows bladder tumor growth in mice.

Autophagy in cancer is a double-edged sword: It protects cells from malignant transformation, but once tumors form, it helps them thrive.

Natural killer cells offer safe and effective cancer treatment, but to succeed in the clinic, they need a bit of an energy boost.

Researchers discovered that copper induces cytotoxicity through a distinct pathway termed cuproptosis. This insight guides the use of copper-shuttling drugs to treat copper regulation disorders and opens up new therapeutic applications for cancer.

Researchers publish new data on the enzyme glyoxalase II and its role in cellular metabolism