Analysis of two pivotal Yescarta clinical trials revealed that patients' germline DNA influences both toxicity risk and CAR T expansion, opening new opportunities for smarter cell therapy design.
Positive results for GLP-1 drugs in alcohol use disorder, a new collaboration to advance in vivo CAR T therapies, Phase 3 readouts in oncology, rare disease, and vitiligo, and more led the news this week.
As deep B cell depletion moves into autoimmune disease, antibody-directed allogeneic NK cell therapy may offer a different path to potency, scalability, and outpatient treatment.
As soaring costs and logistical complexity strain traditional cell therapy models, in vivo CAR T is prompting a fundamental rethink of how advanced therapies are manufactured and scaled.
A first-of-its-kind CAR T treatment helped a woman achieve year-long remission from three severe autoimmune diseases that resisted nine prior therapies.
At the Advanced Therapies conference, industry leaders showcased how in vivo CAR T cell and gene delivery innovations could transform accessibility and clinical outcomes.