Initially thought of as a DNA-damaging drug, 5-fluorouracil mainly kills cancer cells by interfering with ribosomal RNA, opening up new avenues for care.
Profiling over 100,000 genomes, researchers identified rare mutations associated with early menopause and cancer, and that some mutations pass down to children.
A changing dance of transcription factors modulates T regulatory cell gene expression in different immune contexts with implications for cancer and autoimmune diseases.