cancer

Cowpea mosaic virus stimulated the immune system to treat and prevent metastatic cancers in mice.

A changing dance of transcription factors modulates T regulatory cell gene expression in different immune contexts with implications for cancer and autoimmune diseases.

Manish Sharma led a clinical trial for a new antibody-drug conjugate that decreased tumor size in patients who had not responded to chemotherapy.

Breast cancer cells can pass through the bone marrow to reach the tissues surrounding the brain and spinal cord in mice — a new way for cancer to spread.

Bacteria can invade colorectal cancer tumors, leading to worse disease outcomes. Oxygen — or lack thereof — plays a vital role in this interaction.

Avoiding skin cancer could be as easy as slathering on a gel that the body rapidly metabolizes.

Natural killer cells can sometimes attack beneficial CAR T cell immunotherapies. Now, researchers have discovered why and a potential way to stop them.

Cancer cells with mutated p53 undergo apoptosis by stalling ribosomes at rare leucine codons, inhibiting protein translation.

Researchers develop sensitive blood-based diagnostics to detect tiny traces of cancer. 

3D bioprinted models of the tumor microenvironment could make the preclinical research process more reliable and accelerate translation to the clinic.