Cancer

Classical model systems such as cell culture and mice are key to understanding cancer. But what can we learn by examining how cancer works in other models? Animals like naked mole rats and Tasmanian devils offer a new perspective on how cancer works and how we can treat it.

Fetuses transfer some of their cells to their mother in a phenomenon called microchimerism

A new molecule in Phase 1 clinical trials kills leukemia cells by blocking their ability to repair DNA.

Epidemiologists may have found the perfect method to delineate if long-term use of antihypertensive medications increases cancer risk.

Using a mouse model of breast cancer brain metastasis, researchers showed that tumor cells require fatty acid synthesis to grow, which offers a potential therapeutic target.

Targeting oncogenic transcription factors like MYC is challenging, but researchers found a way to target its regulator, WDR5, for degradation, exemplifying the capacity of protein degraders to target the “undruggable.”

Peptide drug targets two cancer proteins for increased specificity and uptake

Once thought of as a regenerative panacea, stem cell research now centers on augmenting and supporting the body’s systems. Adult stem cells play critical roles in maintaining tissue homeostasis throughout development. When this equilibrium is disrupted, disease and cancer may occur. This webinar will examine how stem cell-host interactions boost natural processes and restore physiological homeostasis.A Supporting Role for Stem Cells in Homeostasis

InteRNA publishes preclinical data from investigational microRNA program