blood-brain barrier

The gene therapy treats the rare genetic disease AADC deficiency by delivering a functional gene into the brain.

An oligonucleotide transport vehicle could transform neurological disease treatment by enhancing drug delivery across the blood-brain barrier.

Researchers discovered that a blood clotting protein, fibrinogen, harms brain development during bleeds in preterm infants.

New gene therapies in clinical trials seek to treat Alzheimer’s disease and heal the brain with a dose of helpful genetic material.

Rett syndrome currently has no cure. Now, innovations in gene therapy bring the possibility of treating the root cause of the disease closer than ever before.

The therapy met its primary endpoints in two Phase 3 studies and offers a new approach for the tens of millions of people living with the psychiatric condition.

New research aims to make antibody drug delivery as precise and efficient as the antibodies themselves.

A specific blood-brain barrier protein may present a potential target for treatment-resistant epilepsy. 

Scientists and clinicians discussed their solutions for overcoming the challenge of getting past the blood-brain barrier in DDN’s first seminar.

By using extracellular vesicles to target specific neurons in the hypothalamus, scientists induced weight loss in a mouse model of obesity without altering its diet or exercise.