bioengineering

Nanobodies that bacteria secrete only in the presence of a biomarker treat inflammatory bowel disease at the site of inflammation.

Proteins from intracellular pathogens can help expel drugs delivered by macrophages.

3D bioprinted models of the tumor microenvironment could make the preclinical research process more reliable and accelerate translation to the clinic. 

A new wound dressing monitors infections in real time and administers timely treatment using metal ions.

Researchers investigated the feasibility of microbiome-based drug delivery as a longer-lasting alternative to current topical formulations.

Researchers developed a novel approach for activating neutrophils and boosting anti-tumor immunity.

Fully synthetic approaches expand the repertoire of possible antimicrobials to overcome existing antibiotic resistance mechanisms.

Microbiome researcher Sarah Lebeer studies how beneficial bacteria can help treat inflammatory skin conditions such as acne and atopic dermatitis.

An off-the-cuff request at the local butcher led to a serendipitous discovery about heart valve disease, leading to potential new sex-specific ways to treat it.

Experts discussed the major hurdles of AAV gene therapy, including immunogenicity, vector design, and AAV variability.