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3D illustration of multiple colourful proteins.

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Carterra

Advances in multichannel SPR instruments are moving kinetic analysis from secondary validation to primary screening, generating richer data for AI-driven discovery and lead selection.

Bringing real-time kinetics into large-scale drug discovery workflows in the age of AI

Industry Perspectives

Illustration of the four levels of protein structure, including primary, secondary, tertiary, and quaternary structure

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A 3D rendering showing a drug molecule bound to a protein, symbolic of structure-based protein design.

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A 3D rendering showing a drug molecule bound to a protein, with the protein depicted as a cartoon model and the drug as a ball-and-stick model

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A flowchart illustrating the overall approach to computational protein structure prediction, starting with a protein sequence and progressing through multiple sequence alignment, database searching, secondary structure prediction, protein threading, homology modeling, and  Ab initio modeling to generate a 3D protein model, with steps varying based on the presence of homologs in the PDB and prediction results.

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The cryo-EM structure of a protein is depicted in ribbon and surface representations, with different colors highlighting individual domains within the structures.

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A cartoon representation of a protein binding to a small molecule at the protein’s binding site 

An image of protein crystals used for X-ray crystallography

A cartoon representation of a zinc finger motif of proteins

Learn how <strong id="isPasted">structure-based drug design</strong> uses a protein&#39;s 3D structure to create precisely targeted medicines. Explore the key techniques, from X-ray crystallography to AI-powered modeling.

The power of structure-based drug design

Articles

Gloved researcher transferring liquid into a microplate using a multichannel pipette.

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INTEGRA Biosciences

Discover practical strategies to improve pipetting accuracy, reproducibility, ergonomics, and instrument performance across diverse laboratory workflows.

A practical guide to better pipetting

Ebooks

Multichannel pipette dispensing a serial dilution into a 96-well microplate.

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Discover practical strategies for performing reliable serial dilutions with optimized liquid handling and mixing.

Optimizing automated workflows for serial dilutions

Application Note

Serial dilution series in microcentrifuge tubes showing progressively decreasing concentrations of a purple solution.

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Learn best practices for improving the accuracy, precision, and reproducibility of automated serial dilution workflows.

binding sites

Bringing real-time kinetics into large-scale drug discovery workflows in the age of AI

The power of structure-based drug design

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