Illustration of an engineered T cell in blue binding to a leukemic cell in red. 

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CRISPR-edited immune cells may help patients with T-cell leukemia, albeit with immunotherapy-related risks.

Base editing to treat leukemia in children

News

A flask with bright blue liquid in it sits on a laboratory bench, and rows of empty flasks sit in rows behind it.

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Kan Cao kneels next to a progeria patient in a wheelchair at the 2022 International Progeria Workshop meeting.

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Kan Cao studies the rare aging disorder progeria to find a cure, and she&rsquo;s ready to solve the mysteries of healthy human aging along the way.

From dye to base editing, early aging may soon have a cure

Articles

Krishanu Saha, a biomedical engineer at the University of Wisconsin-Madison, stands near a computer in his lab next to one of his students who sits at a microscope.

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A fluorescent image of an eye with the retina in dark blue and the BDNF receptor in light blue is shown against a black background.

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Keith Martin, a gene therapy researcher at the Centre for Eye Research Australia, stands in a blue suit in front of a grey background.

Creative solutions may enable gene therapy for more common diseases.

Multiple mutations may no longer stump gene therapies

Tools & Techniques

A person is wearing a white lab coat and glasses and is smiling at the camera.

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On the road to treating mitochondrial disease

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A person wearing glasses and a blue check dress shirt is smiling at the camera.

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Carlos Moraes, a mitochondrial biologist at the University of Miami Miller School of Medicine, pioneered restriction endonucleases for degrading mutant mitochondrial DNA. 

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The human mitochondrial genome, inherited matrilineally, is a 16,569-base-pair circular molecule that encodes 37 genes involved in critical mitochondrial functions like adenosine triphosphate (ATP) production. 

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Recent advancements in mitochondrial genome editing technologies take scientists one step closer to developing viable treatments for mitochondrial diseases, which affect 1 in 4300 adults.

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November 2024

A silhouette of a man gazing at the Milky Way, symbolizing spatial biology where scientists explore the spatial arrangement of cells

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10x Genomics

Spatial biology adds a new layer of knowledge to unsolved biological questions.

Journeying through cells&#39; spatial dimensions&nbsp;

Compendium

A conceptual illustration of a drug capsule filled with microchips, representing the integration of artificial intelligence in drug discovery and development

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MilliporeSigma

Learn practical strategies for using artificial intelligence to find the best drug candidate.

A Technology Guide for AI-Enabled Drug Discovery

Technology Guides

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Thermo Fisher Scientific

Advanced LIMS software helps researchers reliably manage complex bioanalytical workflows and data.&nbsp;

base editing

Base editing to treat leukemia in children

From dye to base editing, early aging may soon have a cure

Multiple mutations may no longer stump gene therapies

On the road to treating mitochondrial disease

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Journeying through cells' spatial dimensions

A Technology Guide for AI-Enabled Drug Discovery

Achieving bioanalytical precision and control

November 2024