Two new animal microphysiological system models have been introduced to improve the translatability of preclinical drug safety assessments by enabling early, comparative evaluation of hepatotoxicity across human, rat, and dog Liver-on-a-chip models.
Promising new data shows that Factor H (CPV-104) significantly reduces inflammation and retinal degeneration in an animal model of dry age-related macular degeneration
A changing dance of transcription factors modulates T regulatory cell gene expression in different immune contexts with implications for cancer and autoimmune diseases.
There is no vaccine against this parasitic worm infection, but rhesus macaques’ unique immune system has brought the prospect of a vaccine closer than ever.
Learn how molecular dynamics, AI-aided design, and structural insights combine to reshape how therapeutic proteins are created, validated, and optimized.