animal models

Natural killer cells can sometimes attack beneficial CAR T cell immunotherapies. Now, researchers have discovered why and a potential way to stop them.

Evaluating drug toxicity to development and reproduction is a critical component of drug safety assessment. 

Researchers discovered that a cytokine surge during mid-gestation in mice influenced anxiety behavior in offspring.

Researchers halted sperm production in mice using an existing drug, offering hope for a future male contraceptive pill.

An understudied melanoma arises without sun exposure, but researchers are beginning to shed light on this challenging form of skin cancer. 

Targeting a gut microbial enzyme could potentially improve treatment for type 2 diabetes.

A new porcine model for the rare neurological disorder CLN3 Batten disease more faithfully recreates human symptoms and could accelerate drug development.

Inhibiting an enzyme variant that contributes to severe COVID-19 in men holds promise for treating SARS-CoV-2 infections. 

Different animal models offer unique advantages for specific drug development applications. 

Tardigrades survive heat, freezing, and even space radiation. Now, researchers translate lessons learned from these creatures into more stable drug formulations and new health insights.