Activating specific neurons using light helped scientists establish a causal link between improved sleep and diminished signs of Alzheimer’s disease in mice.
Slight modifications to glycoproteins reveal critical insights into disease onset, state, and progression, making them a wellspring for biomarker discovery.
A small molecule called ALGERNON2 improved health outcomes in mouse models of neurodegenerative diseases by activating antioxidant pathways in astrocytes.
The Alzheimer's disease research field has been beset by failed clinical trials and fraud. But researchers remain hopeful that a better understanding of the disease’s broader picture will lead to treatments.