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3D bioprinted models of the tumor microenvironment could make the preclinical research process more reliable and accelerate translation to the clinic.&nbsp;

Bioprinting tumors to fight them

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The blood brain barrier (BBB) is a selective sheet of endothelial cells lined with a thin basement membrane composed of proteins such as laminin and collagen. The BBB separates the brain from the blood, stopping unwanted blood components from entering the brain. As people age, the BBB becomes more permeable and allows molecules into the brain that damage it. Aran determined that stress-induced damage to red blood cells contributes to BBB degradation.

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When a research question can&rsquo;t be answered using the tools available, bioengineer Kiana Aran makes new tools. Recently, she developed a new type of brain-on-a-chip to answer questions about the blood brain barrier.

Engineers developed a blood brain barrier on a chip

Tools & Techniques

Studying the Response to Cytokines Using Novel In Vitro Stem Cell Platforms

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<p>LIVE October 12th, 2021 at 11:30 AM ET</p><p>Bill Thelin will discuss how intestine-on-a chip technology reliably models gastrointestinal disease and assists researchers in screening for safe, effective therapeutic candidates.</p>

Webinars

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November 2024

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Thermo Fisher Scientific

Advanced LIMS software helps researchers reliably manage complex bioanalytical workflows and data.&nbsp;

Achieving bioanalytical precision and control&nbsp;

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Cytiva

The latest magnetic bead technology cuts sample preparation time, producing consistent, reliable results.&nbsp;

Maximizing NGS efficiency with magnetic beads&nbsp;

Ebooks

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Bio-Rad Laboratories

Advanced gene editing, delivery, and analytical tools are driving better gene therapies.

3D models

Bioprinting tumors to fight them

Engineers developed a blood brain barrier on a chip

Studying the Response to Cytokines Using Novel In Vitro Stem Cell Platforms

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Achieving bioanalytical precision and control

Maximizing NGS efficiency with magnetic beads

Overcoming barriers in gene therapy

November 2024