System combines top-down and bottom-up proteomics to improve biomarker discovery

Bio-Rad Laboratories Inc. and Bruker Corp. have jointly launched the Lucid Proteomics System, the first system to combine top-down and bottom-up proteomics approaches for biomarker discovery.

Register for free to listen to this article
Listen with Speechify
0:00
5:00
Bio-Rad Laboratories Inc. and Bruker Corp.

Bio-Rad Laboratories Inc. and Bruker Corp. have jointlylaunched the Lucid Proteomics System, the first system to combine top-down andbottom-up proteomics approaches for biomarker discovery. With both techniqueson one platform, the Lucid Proteomics System accelerates biomarker researchprograms by improving the chances of discovering biomarkers that have clinicalrelevance. The system combines Bio-Rad's ProteinChip surface-enhanced laserdesorption/ionization (SELDI)-based array technology with Bruker'sultrafleXtreme matrix-assisted laser desorption/ionization time-of-flight(MALDI-TOF/TOF) mass spectrometer. The top-down solution includeshigh-throughput protein profiling and identification of biomarker candidates,either by direct on-chip TOF/TOF analysis suitable for small peptides, or byenrichment, purification and digestion followed by TOF/TOF analysis for largerproteins. For the bottom-up approach, Bruker's ultrafleXtreme MALDI-TOF/TOFoffers unmatched performance with high sensitivity, resolution and massaccuracy. 
 
Bio-Rad Laboratories Inc.
(510) 724-7000

Bruker Corp.

(978) 663-3660
 


Subscribe to Newsletter
Subscribe to our eNewsletters

Stay connected with all of the latest from Drug Discovery News.

March 2024 Issue Front Cover

Latest Issue  

• Volume 20 • Issue 2 • March 2024

March 2024

March 2024 Issue