A 3D-rendered illustration of a eukaryotic cell highlighting organelles such as the nucleus, endoplasmic reticulum, mitochondria, and cytoskeletal structures in pink and purple tones.
Compendium

Shining light on the subcellular proteome

Discover how innovative proteomics tools help researchers peer into once inaccessible organelles, allowing for new targets for drug discovery and development.

Uncovering relevant protein targets and new biomarkers at the exact point of a key cellular interaction is a challenge with existing methods. To understand the cell’s intricate inner workings, researchers need tools that can resolve details at the suborganelle level. Recent innovations in spatial proteomics have enabled researchers to map protein compositions from the smallest and most elusive subcellular structures, offering insights into how their spatial dynamics influence signaling, development, and disease.

Download this application note compendium to learn:

  • High-specificity proteomic strategies for identifying novel proteins in stress granules
  • Precision photolabeling techniques to extract proteomes from nanoscopic organelles such as primary cilia
  • How spatial proteomics supports the discovery of cellular mechanisms underlying stress response, signaling, and intracellular transport

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