Uncovering relevant protein targets and new biomarkers at the exact point of a key cellular interaction is a challenge with existing methods. To understand the cell’s intricate inner workings, researchers need tools that can resolve details at the suborganelle level. Recent innovations in spatial proteomics have enabled researchers to map protein compositions from the smallest and most elusive subcellular structures, offering insights into how their spatial dynamics influence signaling, development, and disease.
Download this compendium to discover how microscopy-guided photolabeling and mass spectrometry techniques can unlock the proteomes of primary cilia and stress granules with exceptional specificity and depth and accelerate drug discovery.
