Optical Coherence Tomography receives a 2023 Lasker Award
James Fujimoto, Eric Swanson, and David Huang developed optical coherence tomography, which transformed ophthalmological practice and spurred new imaging applications.
Rare & Genetic Diseases
A gene therapy hope for halting Huntington’s disease
A one-time gene therapy aims to stop Huntington's disease at its source. But first, it has to survive clinical trials.
2024 Breakthrough Prizes in Life Sciences
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
A vision of the future: Stem cells offer hope for retinal degeneration
Cell therapies derived from stem cells could one day prevent vision loss or even restore sight in retinal degenerative disease.
Powering up cells to power down corneal disease
Injecting healthy, exogenous mitochondria into the eye could combat mitochondrial dysfunction and cell death in Fuchs endothelial corneal dystrophy.
A rare genetic mutation protects against Alzheimer’s disease
Data from a highly resilient individual guided researchers to new potential therapeutic targets.
From the cancer research bench to the vascular disease bedside
A search for a new cancer mouse model turned into the first ever treatment for a rare disease called venous malformations.
Innovating gene therapy delivery
Innovative carriers and delivery strategies may improve gene therapy efficacy and safety.
An in utero stem cell transplant for alpha thalassemia
Alpha thalassemia was once a fatal diagnosis. Now, a clinical trial tests if administering a mother’s stem cells in utero may cure kids before they’re born.
The intricate design of a fundamental filter protein
A collaboration of nephrologists and biochemists created the first structure of “megalin,” a critical protein in kidney and brain disorders.
