| 2 min read
Register for free to listen to this article
Listen with Speechify
0:00
2:00
MENLO PARK, Calif.—Pacific Biosciences of California, Inc.and Roche Diagnostics have signed an agreement to develop diagnostic products,including sequencing systems and consumables, based on Pacific Biosciences'Single Molecule, Real-Time technology. Pacific Biosciences will develop andmanufacture certain products for clinical use, which will be sold exclusivelyto Roche, who has obtained worldwide rights to exclusively distribute saidproducts in the field of human in-vitrodiagnostics. Pacific Biosciences will continue marketing its products for allfields outside of human in-vitrodiagnostics.
 
"We are delighted to have Roche as our in-vitro diagnostics partner," Mike Hunkapiller, presidentand CEO of Pacific Biosciences, said in a press release. "As a world leader in in-vitro diagnostics, Roche brings valuable expertise indesigning products for clinical use and obtaining regulatory approvals to sellclinical products in the U.S. and around the world. We believe the combinationof our SMRT Sequencing technology with Roche's market position and expertise indiagnostics will allow accelerated commercial success for both companies."
 
 
Per the terms of the agreement, Roche will pay PacificBiosciences $35 million up front, with the possibility of up to an additional$40 million in funding if development milestones are met. Once developmentprograms have been completed, Pacific Biosciences expects additional incomefrom the manufacture and supply of instrument, software and some consumableproducts, which Roche will market and distribute for clinical use inconjunction with its assay-specific reagents.
 
 
"We see great potential in Pacific Biosciences' sequencingtechnology for the development of future clinical sequencing applications," DanZabrowski, head of the Sequencing Unit at Roche, commented in a statement."Sequencing will be a key technology in addressing the strong and growingdemand for genetic and genomic solutions in the clinic. We are looking forwardto this partnership to accelerate and support the transition of DNA sequencinginto routine diagnostics through our joint development efforts."
 
 
This is Pacific Biosciences' second recent partnership featuring its Single Molecule, Real-Time technology. In May, the companyannounced a co-marketing partnership with Sage Science, under which thepartners will provide customers of the PacBio RS II DNA Sequencing System withthe ability to sequence even longer fragments of DNA when performing SingleMolecule, Real-Time Sequencing. Utilizing Sage Science's BluePippin platform,which is part of a line of automated size-selection tools, optimizessequencing. Scientists at Pacific Biosciences assessed threelibraries—bacterial, fish and mammalian—generated with and without BluePippinsize selection, and with BluePippin, N50 subread lengths increased by 90percent, 110 percent and 86 percent respectively.
 
 
 
SOURCE: Pacific Biosciences press release

About the Author

Related Topics

Loading Next Article...
Loading Next Article...
Subscribe to Newsletter

Subscribe to our eNewsletters

Stay connected with all of the latest from Drug Discovery News.

Subscribe

Sponsored

Gold circles with attached purple corkscrew shapes represent gold nanoparticles against a black background.

Driving gene therapy with nonviral vectors 

Learn why nonviral vectors are on the rise in gene therapy development.
A 3D digital illustration of a viral spike protein on a cell surface, surrounded by colorful, floating antibodies in the background

Milestone: Leapfrogging to quantitative, high throughput protein detection and analysis

Researchers continuously push the boundaries of what’s possible with protein analysis tools.
Blue cancer cells attached to a cellular surface against a bright blue background in a 3D rendering of a cancer infection.

Advancing immuno-oncology research with cellular assays

Explore critical insights into immunogenicity and immunotoxicity assays for cancer therapies.
Drug Discovery News November 2024 Issue
Latest IssueVolume 20 • Issue 6 • November 2024

November 2024

November 2024 Issue

Explore this issue