Adeno-associated virus (AAV) gene therapy shows great promise for disease treatment, but pre-existing neutralizing antibodies within hosts may hinder gene therapy delivery to target tissues and interfere with gene therapy re-administration. In this webinar, Jayoung Kim will discuss new approaches to evade AAV neutralizing antibodies and improve genetic cargo delivery to target tissues, including anchoring AAVs to red blood cells and using non-viral nanoparticles as gene therapy carriers.
Topics to be covered
- Overcoming targeting and immunological barriers for AAV-mediated gene therapy
- Understanding the difference between biodistribution and successful transgene expression
Wednesday, August 30th 2023 | 2:30 PM - 3:30 PM Eastern Time
This webinar will be available to view live and on demand.
Speaker
Jayoung Kim, PhD
Assistant Professor
University of North Texas Health Science Center