An understanding of the patent history and intellectual property landscape surrounding the use of the CRISPR/Cas9 system is critical for any researcher considering designing a mouse or rat model using this technology
Syngeneic mouse models are employed extensively in early-stage drug discovery and have become a workhorse for one of the fastest-growing areas of research, immuno-oncology, transforming how investigators approach novel therapies
In efforts to improve upon the human relevance of mouse-based studies, investigators are increasingly turning to models with
genetically introduced human components