NexMR is a Swiss startup spinning off ETH Zürich and operating at the forefront of NMR drug design, with facilities in Schlieren, Switzerland. NexMR’s unique hyperpolarized NMR screening platform can measure up to 700 samples daily to supercharge AI drug design models with accurate hit / not hit lists, affinities, and binding epitopes. The platform encompasses Cryolight® a light source for automated ultrafast NMR data collection on NMR spectrometers equipped with cryogenic probes, and NMRQuest® a software for photohyperpolarized NMR sample management and data analysis. NexMR's technology is versatile and delivers data for many targets, including membrane and intrinsically disordered proteins.
A breakthrough from AI|ffinity and NexMR was achieved with a 100-fold affinity improvement in the initial round of drug discovery using ultrafast NMR screening and AI-driven lead generation against intrinsically disordered protein targets.
Explore how emerging in vitro systems — built from primary cells, cocultures, and vascularized tissues — are improving translational research outcomes.