Neuroscience

A 3D rendering of voltage-gated sodium channel Nav1.7 (shown as a blue blob structure) embedded into a membrane next to regulatory protein CRMP (shown as a ribbon diagram encased within a yellow blob). A yellow region within the Nav1.7 structure signifies the CRMP binding site.

A gene therapy for chronic pain

Researchers identified a peptide that selectively blocks pain signaling in sensory neurons and packaged it into a viral-based gene therapy in a step towards treating chronic pain without the risk for addiction.
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