Induced pluripotent stem cells (iPSCs), differentiated cells reprogrammed into a stem cell-like state, hold promise for precision medicine, but they may also serve as a renewable source for off-the-shelf cell therapies. This approach would allow researchers to take ready-made iPSCs and genetically manipulate them to treat different diseases. However, transplanting these cells still carries the risk of immune rejection.
Download this research summary from Bio-Techne to learn how a team of scientists generated immunologically undetectable iPSCs for large-scale manufacturing of universally compatible cell therapies.