September 2023 Volume 19, Issue 8

Volume 19, Issue 8 | September 2023
September 2023
In this Issue
Hematology

From the cancer research bench to the vascular disease bedside
A search for a new cancer mouse model turned into the first ever treatment for a rare disease called venous malformations.
Targeting microbes to treat heart disease
Inhibitors that target gut microbial enzymes are likely the key to treating a variety of cardiovascular diseases, some of which have no other cure.
Filtering out cancer’s invisibility cloak
By removing immunosuppressive factors from the blood, researchers hope to give the immune system a fighting chance against advanced tumors.Metabolic Disease

Biomaterials for better diabetes cell therapy
Aiming to restore insulin function in type 1 diabetes, Lonnie Shea develops scaffolds that support the growth and transplantation of pancreatic islet structures.Ophthamology

Powering up cells to power down corneal disease
Injecting healthy, exogenous mitochondria into the eye could combat mitochondrial dysfunction and cell death in Fuchs endothelial corneal dystrophy.
A vision of the future: Stem cells offer hope for retinal degeneration
Cell therapies derived from stem cells could one day prevent vision loss or even restore sight in retinal degenerative disease.Editor's Focus

Explained: How does the body process oral medications?
Upon ingesting drugs, a complex cascade of physiological events unfolds within the body.
Science Milestone: The rise of Herceptin
Herceptin transformed breast cancer treatment and opened the door to targeted therapy.
Basic science: a key ingredient in innovation
From green fluorescent protein to polymerase chain reaction, many basic science discoveries fueled important advances in biomedicine.Cancer

Chemotherapy’s hidden origins
From chemical warfare trenches, scientists glimpsed an opportunity to transform deadly mustard gas into a revolutionary cancer treatment.

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