September 2012- Volume 8, Issue 9

September 2012

In this Issue

Commentary

CDx, cancer and collaborations: Take our reader survey

CDx, cancer and collaborations: Take our reader survey

Drug Discovery News, in collaboration with investment bank Mizuho Securities USA Inc., is conducting a survey on the state of funding and views on companion diagnostics, oncology and pharma.

Out of Order: If you build it …

Out of Order: If you build it …

Where companies traditionally have had to jump through hoops to impress regulators to approve the drugs they develop, they will increasingly find themselves jumping through even narrower hoops to convince payors that they have made significant strides in improving patient care.

Research & Development

Stem cells on the brain

Stem cells on the brain

Duke to examine Cytomedix stem cell treatment for glioma patients

Attention to detail

Attention to detail

P2D Biosience, Advinus Therapeutics to develop unique therapies for ADHD

Looking to build a bit of synergy

Looking to build a bit of synergy

Synergy Pharmaceuticals to formally merge with Callisto Pharmaceuticals

T cell targets

T cell targets

Brigham and Women’s Hospital and Sanofi collaborate on immunomodulation of type 1 diabetes

Disease in a dish

Disease in a dish

NYSCF research programs skin cells into Alzheimer’s disease brain cells

Tools & Technology

AstraZeneca goes virtual

AstraZeneca goes virtual

Virtual lab from Assay Depot enables full project tracking via computer

One byte at a time

One byte at a time

MSU researchers develop new computational technique to manage massive amounts of data on microbes

A multiplex menu

A multiplex menu

Bio-Rad and Myriad RBM partner to commercialize multiplex biomarker kits

A pair for the win

A pair for the win

Waters Corp. and Nonlinear Dynamics combine analytical science and informatics skills to advance proteomics and metabolomics research

Tiny brain, huge potential

Tiny brain, huge potential

Vanderbilt University-led team to develop ‘microbrain’ to improve drug testing

Feature

Meeting of the minds

Meeting of the minds

Neuroscience 2012 offers five days of cutting-edge research, networking, career opportunities and more in New Orleans

Diagnostics

From under the sea

From under the sea

Myriad Genetics and Pharma Mar ink companion diagnostic agreement

GenMark goes ALL-digital

GenMark goes ALL-digital

GenMark Diagnostics and Advanced Liquid Logic to develop an all-digital fully integrated diagnostic platform

High risk, high payoff

High risk, high payoff

Metabolon, Lipomics Technologies combine forces to fight obesity, cancer

A partnership with a firm Foundation

A partnership with a firm Foundation

Foundation, Clovis to develop in-vitro diagnostic for PARP inhibitor

Change of Life

Change of Life

Life Technologies acquires Pinpoint Genomics and CLIA-approved lung cancer test

Global News

Synergy among neighbors

Synergy among neighbors

Quintiles acquires Expression Analysis to advance safety, efficacy and value of personalized medicine

Lonza announces license agreement with iPS Academia Japan

Lonza announces license agreement with iPS Academia Japan

Company adds iPSC line to its portfolio of cell therapy products and services

Calling the X-MAN to battle cancer gene

Calling the X-MAN to battle cancer gene

Horizon Discovery and Domainex to explore lead molecules against TBK1/IKKe

All systems Funxional

All systems Funxional

Boehringer Ingelheim acquires Funxional’s somatotaxin anti-inflammatory program

Government Watch

Second verse, same as the first

Second verse, same as the first

ACLU and PUBPAT argue in vain in appeals court against patents on breast cancer genes

Stem cells can be regulated as drugs, court says

Stem cells can be regulated as drugs, court says

Judge sides with FDA in four-year battle over stem cell therapy use by Colorado company

Sun comes out for orphan diseases

Sun comes out for orphan diseases

FDA Safety and Innovation Act paves way for fast-tracking new treatments for rare conditions

Curing disease at the genetic level

Curing disease at the genetic level

European regulators poised to approve Western world’s first-ever gene therapy treatment

Omics & Systems Biology

Circuit-makers target genetic bottlenecks

Circuit-makers target genetic bottlenecks

MIT researchers build a ‘toolbox’ for synthetic biology to help control novel genetic circuits in cells

Study unveils genetic underpinnings of PTSD

Study unveils genetic underpinnings of PTSD

BUSM/VA Boston Healthcare System investigators identify new gene linked to post-traumatic stress disorder

Closing the circle on Huntington’s disease

Closing the circle on Huntington’s disease

Thomson Reuters to collaborate with the CHDI Foundation to develop new tools to battle Huntington’s disease

Going after GPCR

Going after GPCR

Anchor Therapeutics collaborates with Kyowa Hakko Kirin for pepducin R&D

Editor's Focus

Genetic therapies? The heck, you say!

Genetic therapies? The heck, you say!

Gene therapies have been somewhat of an urban legend in the pharma/biotech industries for almost as long as I have been alive. Despite how far we’ve come and how far we’ve yet to go, we’re reporting some stories this month that suggest genetic medicine may not be as science fiction-y as it seems.
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