September 2011 Volume 7, Issue 9

Volume 7, Issue 9 | September 2011

September 2011

In this Issue

Research & Development

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Getting fired up for fibrotics

Acquisition of Amira nets BMS fibrosis, inflammation candidates
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Unwilling to deal

AMAG rejects MSMB acquisition bid, sticks with plans for Allos merger
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ACE in the hole

Acceleron Pharma launches global collaboration with Celgene on ACE-536 drug to treat anemia
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Buying pains

Pfizer proposes to acquire pain-treatment collaborator Icagen in transaction valued around $56 million
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A cure for the common cold?

MIT team crafts drug that could treat broad spectrum of viral infections
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Going more than skin deep

Gladstone scientists transform adult skin cells into brain cells

Government Watch

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Stem cell case is dismissed

Court throws out Sherley case; government funding of hESC research continues
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Patents prevail in Myriad case

ACLU disputes Federal Circuit decision allowing patents on breast cancer genes, other human genes
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With biosimilars, close counts

But getting close will require a new, more vigorous review process
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Left hand, meet right hand

Democratic Congressional reps urge United States not to propose limiting international trade language; Republicans counter with their own missive to the president
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NIH finalizes financial conflict of interest rules

In late August, the National Institutes of Health (NIH) finalized rules to reduce financial conflicts of interests among federally funded researchers who also receive payments or stock from drug and medical device companies.

Omics & Systems Biology

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Double-down with ChK-1

Array and Genentech announce new oncology deal that will explore both companies\' checkpoint kinase 1 candidates
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Sequencing 500 human genomes—just like that

Illumina and University of Oxford collaborate in search for genetic basis of rare diseases
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A matter of expression

Covance, Broad Institute to collaborate on sequencing genome studies
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All in the delivery

Alnylam and MIT discover novel ‘core-shell’ nanoparticles for systemic delivery of RNAi therapeutics
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Say ‘ah’ and become part of history

Kaiser, UC San Francisco working on gene catalog of healthcare members

Diagnostics

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Not a done deal

Alere acquires stake in Axis-Shield, but the Dx test developer rejects possible takeover
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Going with the flow

Oral fluid diagnostics provider DNA Genotek scooped up by OraSure
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Exosomes and real life

New England Peptide and Atlantic Cancer Research Institute file joint patent application for new peptides that support targeted diagnosis and therapies
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Biomarker-based blood test

BioMarCare Technologies receives $900K grant for joint project with Ariadne to develop colorectal cancer test
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To the max

BD, Lab21 partner to develop aspergillus assay
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QIAGEN and Pfizer partner on companion Dx for lung cancer

QIAGEN announced Aug. 16 that it has entered into a partnership with Pfizer Inc. for the development of a companion molecular diagnostic test for use with an investigational Pfizer compound in global clinical development for treatment of non-small cell lung cancer (NSCLC).

Commentary

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Guest Commentary: Every drug deserves a second chance

How drug repositioning could be an industry game changer

Patent News

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Embryonic stem cell funding suit is dead

The Sherley v. Sebelius lawsuit was dismissed by a federal judge after an appeals court found the government-backed research is probably lawful. In a related move, lawmakers in Congress have reintroduced legislation to support hESC research.

Editor's Focus

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ddn’s ‘summer of stem cells’

From collaborations between the world’s top pharmas and biotechnology companies, to groundbreaking preclinical research, to the development of new tools to be used in stem cell research labs, ddn has become a veritable “Situation Room” for stem cells.

Global News

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Aiming at a target

Intercept, Servier in deal to develop diabetes drug
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Far East pharma deal

Dr. Reddy’s acquires JB Chemicals & Pharmaceuticals prescription business in Russia, other CIS markets
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A world divided

Trius Therapeutics and Bayer will collaborate on worldwide development and commercialization of Trius’ anti-infective torezolid phosphate
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‘Oxford of the East’ meets pharma of the West

Merck and Serum Institute collaborate on pneumococcal conjugate vaccine
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Valeant trumps Paladin's offer for Afexa

Afexa Life Sciences Inc. has learned that sometimes, being picky pays off.

Instruments & Informatics

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Easing the growing pains

Coriell Institute teams with IBM to advance personalized medicine efforts
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Reverse, then forward

GNS Healthcare to create inflammation disease models for Bristol-Myers Squibb
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Image is everything

Analysis software for umbilical cord blood focus of new partnership
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Brooks buys into biobanking

Automation company announces purchase of Nexus Biosystems

Feature

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Staking a claim

Growing stem cell market entices Big Pharma to harness its power for drug screening, toxicity testing
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Blazing the trail

Backed by strong venture capital funding, biotechs organize around promise of stem cell research
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Best in class

A roundup of North America\'s top five academic research institutions in the stem cell arena
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Tools of the trade

Life science tool providers provide constant support to ever-evolving stem cell research community
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