September 2011- Volume 7, Issue 9

September 2011

In this Issue

Research & Development

A cure for the common cold?

A cure for the common cold?

MIT team crafts drug that could treat broad spectrum of viral infections

Going more than skin deep

Going more than skin deep

Gladstone scientists transform adult skin cells into brain cells

Unwilling to deal

Unwilling to deal

AMAG rejects MSMB acquisition bid, sticks with plans for Allos merger

ACE in the hole

ACE in the hole

Acceleron Pharma launches global collaboration with Celgene on ACE-536 drug to treat anemia

Buying pains

Buying pains

Pfizer proposes to acquire pain-treatment collaborator Icagen in transaction valued around $56 million

Getting fired up for fibrotics

Getting fired up for fibrotics

Acquisition of Amira nets BMS fibrosis, inflammation candidates

Feature

Blazing the trail

Blazing the trail

Backed by strong venture capital funding, biotechs organize around promise of stem cell research

Best in class

Best in class

A roundup of North America\'s top five academic research institutions in the stem cell arena

Tools of the trade

Tools of the trade

Life science tool providers provide constant support to ever-evolving stem cell research community

Staking a claim

Staking a claim

Growing stem cell market entices Big Pharma to harness its power for drug screening, toxicity testing

Omics & Systems Biology

All in the delivery

All in the delivery

Alnylam and MIT discover novel ‘core-shell’ nanoparticles for systemic delivery of RNAi therapeutics

Say ‘ah’ and become part of history

Say ‘ah’ and become part of history

Kaiser, UC San Francisco working on gene catalog of healthcare members

Sequencing 500 human genomes—just like that

Sequencing 500 human genomes—just like that

Illumina and University of Oxford collaborate in search for genetic basis of rare diseases

A matter of expression

A matter of expression

Covance, Broad Institute to collaborate on sequencing genome studies

Double-down with ChK-1

Double-down with ChK-1

Array and Genentech announce new oncology deal that will explore both companies\' checkpoint kinase 1 candidates

Global News

Aiming at a target

Aiming at a target

Intercept, Servier in deal to develop diabetes drug

Far East pharma deal

Far East pharma deal

Dr. Reddy’s acquires JB Chemicals & Pharmaceuticals prescription business in Russia, other CIS markets

A world divided

A world divided

Trius Therapeutics and Bayer will collaborate on worldwide development and commercialization of Trius’ anti-infective torezolid phosphate

‘Oxford of the East’ meets pharma of the West

‘Oxford of the East’ meets pharma of the West

Merck and Serum Institute collaborate on pneumococcal conjugate vaccine

Valeant trumps Paladin's offer for Afexa

Valeant trumps Paladin's offer for Afexa

Afexa Life Sciences Inc. has learned that sometimes, being picky pays off.

Instruments & Informatics

Easing the growing pains

Easing the growing pains

Coriell Institute teams with IBM to advance personalized medicine efforts

Reverse, then forward

Reverse, then forward

GNS Healthcare to create inflammation disease models for Bristol-Myers Squibb

Image is everything

Image is everything

Analysis software for umbilical cord blood focus of new partnership

Brooks buys into biobanking

Brooks buys into biobanking

Automation company announces purchase of Nexus Biosystems

Diagnostics

Going with the flow

Going with the flow

Oral fluid diagnostics provider DNA Genotek scooped up by OraSure

Exosomes and real life

Exosomes and real life

New England Peptide and Atlantic Cancer Research Institute file joint patent application for new peptides that support targeted diagnosis and therapies

Biomarker-based blood test

Biomarker-based blood test

BioMarCare Technologies receives $900K grant for joint project with Ariadne to develop colorectal cancer test

To the max

To the max

BD, Lab21 partner to develop aspergillus assay

QIAGEN and Pfizer partner on companion Dx for lung cancer

QIAGEN and Pfizer partner on companion Dx for lung cancer

QIAGEN announced Aug. 16 that it has entered into a partnership with Pfizer Inc. for the development of a companion molecular diagnostic test for use with an investigational Pfizer compound in global clinical development for treatment of non-small cell lung cancer (NSCLC).

Not a done deal

Not a done deal

Alere acquires stake in Axis-Shield, but the Dx test developer rejects possible takeover

Government Watch

Patents prevail in Myriad case

Patents prevail in Myriad case

ACLU disputes Federal Circuit decision allowing patents on breast cancer genes, other human genes

With biosimilars, close counts

With biosimilars, close counts

But getting close will require a new, more vigorous review process

Left hand, meet right hand

Left hand, meet right hand

Democratic Congressional reps urge United States not to propose limiting international trade language; Republicans counter with their own missive to the president

NIH finalizes financial conflict of interest rules

NIH finalizes financial conflict of interest rules

In late August, the National Institutes of Health (NIH) finalized rules to reduce financial conflicts of interests among federally funded researchers who also receive payments or stock from drug and medical device companies.

Stem cell case is dismissed

Stem cell case is dismissed

Court throws out Sherley case; government funding of hESC research continues

Commentary

Patent News

Embryonic stem cell funding suit is dead

Embryonic stem cell funding suit is dead

The Sherley v. Sebelius lawsuit was dismissed by a federal judge after an appeals court found the government-backed research is probably lawful. In a related move, lawmakers in Congress have reintroduced legislation to support hESC research.

Editor's Focus

ddn’s ‘summer of stem cells’

ddn’s ‘summer of stem cells’

From collaborations between the world’s top pharmas and biotechnology companies, to groundbreaking preclinical research, to the development of new tools to be used in stem cell research labs, ddn has become a veritable “Situation Room” for stem cells.
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