September 2009- Volume 5, Issue 9

September 2009

In this Issue

Feature

What’s on your mind?

What’s on your mind?

The Windy City will host the 39th annual meeting of the Society for Neuroscience

Bench Press

Natural-born killers identified by British researchers

Natural-born killers identified by British researchers

A team of British researchers, led by Dr. Hugh Brady of Imperial College London’s Department of Life Sciences and publishing in the journal Nature Immunology in mid-September, have identified the master gene that causes blood stem cells to turn into disease-fighting natural killer immune cells. This is a discovery that the team, which included researchers from University College London and the Medical Research Council’s National Institute for Medical Research, believes could one day help scientists boost the body’s production of these frontline tumor-killing cells, creating new ways to treat cancer.

Automation & Instrumentation

Bringing separations together

Bringing separations together

After several acquisitions and a closed-door transformation, Grace Davison emerges as full-fledged separations business with Reveleris system

Google that virus

Google that virus

Roche lends Google.org technological muscle for efforts centered on better tracking of viruses and preventing their spread

Stretching out a bit

Stretching out a bit

Millipore expands drug discovery and development services in Europe with BioAnaLab acquisition

Firstest with the mostest

Firstest with the mostest

Bruker Daltonics’ mass spec joint venture in India aims at market leadership

Agilent, Varian mum on blockbuster deal

Agilent, Varian mum on blockbuster deal

Proposed $1.5 billion merger would solidify Agilent's position in bio-analytical measurement

Informatics

Data analysis double play

Data analysis double play

Maaguzi and Covance acquisitions solidify Phase Forward’s leadership aims in the integrated clinical research suite market

Picture perfect

Picture perfect

FujiFilm Imaging Colorants selects Dotmatics to provide research data visualization solutions

EDC made easy

EDC made easy

Korea’s DreamCIS selects Oracle Health Sciences software solutions to speed clinical trial data collection

First comes love, then comes marriage

First comes love, then comes marriage

After one-year partnership on Phase I trial electronic data capture solutions, OmniComm acquires EDC assets of Logos Technologies

Silo breakdown

Silo breakdown

Sigma-Aldrich acquires ChemNavigator to give researchers a one-stop shop for compound selection and procurement services

Global News

Sanofi’s booster shot

Sanofi’s booster shot

Sanofi Pasteur strengthens vaccines position in India through control of Shantha Biotechnics

Novartis sponsors Avila Therapeutics’ covalent drug candidate

Novartis sponsors Avila Therapeutics’ covalent drug candidate

Avila Therapeutics Inc. has entered into an option agreement with the Novartis Option Fund focused on Avila’s advancement of a novel covalent drug program from Avila’s research pipeline in conjunction with an equity investment

Transoceanic translational collaboration

Transoceanic translational collaboration

Applied Bio's sequencing technology to be used by Australian university to accelerate pancreatic and ovarian cancer research

Research across the Pacific

Research across the Pacific

AlphaRx and Venturepharm announce agreement to develop drug development center in China

BioFocus DPI, Oncodesign join forces in oncology discovery

BioFocus DPI, Oncodesign join forces in oncology discovery

BioFocus DPI and Oncodesign have pooled their expertise and resources to form a drug discovery service specializing in the rapid generation of promising anticancer drugs

Research & Development

Personalized cancer therapy

Personalized cancer therapy

EMD Serono teams up with M.D. Anderson researchers to accelerate development of effective oncology drugs

Diabetes a sweet spot for collaboration

Diabetes a sweet spot for collaboration

Juvenile Diabetes Research Foundation and Novartis’ Genomics Institute forge diabetes drug partnership

Deterioration detection

Deterioration detection

AstraZeneca, Australia's MHRI collaborate on early detection of Alzheimer's

From Russia with love

From Russia with love

Merck Serono joins Russian-led team at MSM Protein Technologies to raise antibodies to complex cell surface receptors

BMS acquires Medarex for $2.1B

BMS acquires Medarex for $2.1B

Merger is part of 'string of pearls' growth strategy; larger deals may follow

New Products

Biotin-binding microplates with higher sensitivity

Biotin-binding microplates with higher sensitivity

Thermo Fisher Scientific has expanded its line of biotin-binding microplates with the introduction of the Thermo Scientific Pierce High Sensitivity Streptavidin and NeutrAvidin Coated Plates.

Improved efficiency of intracellular delivery of bioactive molecules

Improved efficiency of intracellular delivery of bioactive molecules

Biocompatibles has launched a new product in its CelLuminate range of intracellular delivery systems.

New epoch in spectrophotometer technology

New epoch in spectrophotometer technology

BioTek has launched the Epoch Multi-Volume Spectrophotometer System for monochromator based absorbance measurements in volumes as low as 2 µL.

New mouse stem and primary cells

New mouse stem and primary cells

The Jackson Laboratory has introduced two new research tools—JAX Mouse Embryonic Stem Cells (mES) and JAX Mouse Embryonic Fibroblasts (MEFs). JAX mES cells are self-renewing, non-transformed cell lines established from day 3.5 blastocysts and can differentiate into all three embryonic germ layers: endoderm, ectoderm and mesoderm.

Genomics & Proteomics

Covance picks up Merck lab

Covance picks up Merck lab

Company acquires Seattle-based Gene Expression Laboratory and will provide Merck with genomic analysis services

Genomics on the mind

Genomics on the mind

Lilly and SeqWright team up with a pair of Roche business units to get to genetic roots of psychiatric diseases

Aptamers as a targeting moiety in two deals

Aptamers as a targeting moiety in two deals

Archemix aptamers to carry the payload for miRagen and Dicerna RNA therapeutics

Alnylam, Tekmira target RNAi therapeutics

Alnylam, Tekmira target RNAi therapeutics

In a move aimed at the discovery of novel cationic lipids and lipid nanoparticles for the systemic delivery of RNAi therapeutics, Alnylam Pharmaceuticals Inc. and Tekmira Pharmaceuticals Corp. have joined forces and launched a new company, AlCana Technologies Inc.

Unmasking the villain

Unmasking the villain

University of North Carolina researchers decode the structure of an entire HIV genome

Commentary

Sample management: The elephant in the room?

Sample management: The elephant in the room?

Upgrading sample management and storage can represent a significant initial investment, but the benefits far exceed the costs. By upgrading sample management systems, the “elephant in the room” can be exposed and removed, saving time and money and averting a wide range of problems.

Why study a drug in distilled water when urine is cheaper?

Why study a drug in distilled water when urine is cheaper?

Or is it? This is the title I used at an American Chemical Society symposium on clinical chemistry in the late 1970s. Even in my youth, I was complaining about analytical chemistry faculty doing things that had very little biological relevance, when it was not that hard to do the opposite. Thirty years later, I’ve had to modify my opinion because urine, blood, rats, tissue, saliva and all the rest have recently become very expensive, and properly so.

Editor's Focus

‘Miles to go’ before Kennedy’s vision of healthcare reform is realized

‘Miles to go’ before Kennedy’s vision of healthcare reform is realized

On Aug. 25, Massachusetts Sen. Edward “Ted” Kennedy passed away at the age of 77 after battling a malignant glioma, leaving our nation to celebrate his accomplishments and wonder how his passing will affect Congress’ current healthcare reform proposals.
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