September 2008 Volume 4, Issue 9

Volume 4, Issue 9 | September 2008

September 2008

In this Issue

Research & Development

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Changing the R&D landscape

Lilly sells Greenfield Labs, signs 10-year, $1.6 billion R&D deal with Covance
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Venturing into vaccines

Sanofi Pasteur to buy vaccine supplier Acambis
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Clear kidney connection

Cytochroma, Mitsubishi Tanabe ink deal for chronic kidney disease therapeutics
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What’s old is new again

PhytoMedical to develop Dartmouth’s forgotten cancer compounds
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Making their mark

Biomarker company Clinical Data acquires Adenosine Therapeutics

Global News

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ImClone says no to BMS

Oncology biopharma rejects BMS' $4.5B acquisition offer
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Alpharma: ‘No thanks’ to $1.4 billion offer

King Pharmaceuticals makes unsolicited $33 per share bid for specialty pharma company
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Back in the game

PDL BioPharma inks deal with Bristol-Myers Squibb for multiple myeloma candidate elotuzumab
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Valeant, Meda strike multiple deals

Valeant sells Western, Eastern Europe operations to Meda for $392 million
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MediGene sells European Oracea rights to Galderma

Milestone payments to total up to E32 million

Genomics & Proteomics

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Of mice and HIV models

Researchers come up with a more humanized HIV mouse model
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Focus on the gene scene

Broad Institute releases free Integrative Genomics Viewer
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‘Zoom lens’ for sequencing

TGen and febit collaborate to refine new DNA capture method
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Follow the leader

Alnylam arranges licenses to gain dominant IP position in RNAa
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Rosetta, NIH to ID microRNA drug targets

In a collaboration that aims to find potential drug targets for treating human immunodeficiency virus (HIV) infection, Rosetta Genomics—which has headquarters both in Israel and Jersey City, N.J.—will work with the National Institutes of Health (NIH) to identify microRNAs implicated in HIV viral replication and their function.

Informatics

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The power of Pattern Array

University of Maryland researchers see commercial opportunity for novel data mining software
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Breaking down clinical barriers

Pharsight, CRI Worldwide team up to improve clinical trial efficiency
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A sum greater than its parts

SDI combines forces with Verispan to create comprehensive healthcare industry database
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Clinic-to-research connection

Sealy Center, GenoLogics to develop biomedical informatics solution
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A broader protein vision

Waters teams with Proteome Software for protein visualization

Editor's Focus

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Few bargains in biotech acquisitions

A funny thing happened on the way to the biotech bargain basement the big companies had been picking over, the pharmas and biotechs on display like so many shirts on a clearance rack at Nordstrom’s: the acquisition targets started saying, “No, we don’t want your funny billion dollars, we’re worth more.”

Commentary

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At what cost (overzealous) reactions?

Franklin Roosevelt suggested that “the only thing we have to fear is fear itself.” There are many other things to fear, and one of them is poorly reported medical data.
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Pharma faces Congressional battles in 2009

Industry sees little difference in proposed policies of Obama and McCain

Automation & Instrumentation

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Multi-mode partnership

BioTek and fledgling assay company Gyrasol sign co-marketing agreement
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Custom-made deal

Invitrogen, Lentigen to provide custom lentiviral gene-overexpression products
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Fluorescent tags for live cells

Promega, Leica set sights on sub 100 nm live cell imaging
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Caliper extends screening services

Adds RapidKinase profiling and enzymatic mechanism of action studies

Feature

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Take a really good look

Mining data may be the easy part; visualizing it for proper analysis and development is the big challenge now
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Driving gene therapy with nonviral vectors 

Learn why nonviral vectors are on the rise in gene therapy development.
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Milestone: Leapfrogging to quantitative, high throughput protein detection and analysis

Researchers continuously push the boundaries of what’s possible with protein analysis tools.
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Advancing immuno-oncology research with cellular assays

Explore critical insights into immunogenicity and immunotoxicity assays for cancer therapies.
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