September 2007- Volume 3, Issue 9

September 2007

In this Issue

Automation & Instrumentation

BioServe breaks out: Develops CRC diagnostic with Phenomenome Discoveries, moves into new HQ

BioServe breaks out: Develops CRC diagnostic with Phenomenome Discoveries, moves into new HQ

BioServe announced it had developed a novel serum-based diagnostic test with Canadian company Phenomenome Discoveries for the identification of colorectal cancer (CRC), and moved its home base into a new 40,000-square-foot home office that includes wet and dry labs, and is also the home of its Global Repository of more than 600,000 DNA, tissue and serum samples of Genomics Collaborative.

Cisbio, Lumiphore lighten it up

Cisbio, Lumiphore lighten it up

Cisbio, the developer of HTRF (homogeneous time-resolved fluorescence) technology and start-up biotech, lanthanide specialist Lumiphore Inc., announced early this month an agreement whereby Cisbio will incorporate Lumiphore’s Lumi4 complexes in Cisbio assays.

PerkinElmer launches assay development service

PerkinElmer launches assay development service

PerkinElmer announced early last month the launch of a comprehensive assay development service for high-performance, highly sensitive assays in advanced cellular science and drug discovery research.

Genotyping for the masses: Applied Bio launches genotyping service provider program for core labs

Genotyping for the masses: Applied Bio launches genotyping service provider program for core labs

Looking to both increase the sales of products in its SNPlex line, as well as help its core lab cusotomers provider a wider suite of services to customers, Applied Biosystems Inc. rolled out a service provider program via selected core labs to bring genotyping services to researchers that do not have access to capillary electrophoresis (CE) genetic analysis systems.

Waters boosts position in thermal analysis market with Calorimetry Sciences acquisition

Waters boosts position in thermal analysis market with Calorimetry Sciences acquisition

In a bid to capitalize on the relatively small but growing thermal analysis market in life sciences, Waters Corp. recently acquired Linden, Utah-based Calorimetry Sciences Corp. (CSC), a manufacturer of high-performance calorimeters.

Research & Development

SurModics buys Brookwood for $40 million

SurModics buys Brookwood for $40 million

SurModics Inc. acquired Brookwood Pharmaceuticals Inc. in a move that combines two portfolios of drug delivery technologies rooted in polymers.

Modeling drug toxicity

Modeling drug toxicity

Biological simulations specialist Entelos announced it entered into a CRADA with the U.S. Center for Drug Evaluation and Research (CDER) to develop models of drug-induced liver injury.

Recent recalls push early tox market

Recent recalls push early tox market

In August, Australia’s Therapeutic Goods Administration asked Novartis AG to pull the pain reliever Prexige from store shelves because of a handful of reports about severe liver reactions in patients taking the drug, including two deaths.

Magellan BioScience, Thrombotargets team up for marine-isolated microorganism screening

Magellan BioScience, Thrombotargets team up for marine-isolated microorganism screening

Magellan BioScience Group Inc., and Thrombotargets Corp. recently entered into a drug discovery joint venture agreement that unites an unlimited number of Magellan’s compounds and extracts derived from marine microorganisms with Thrombotargets’ technology for high-throughput screening of pathway activity.

Genomics & Proteomics

A double gain: Epidauros acquisition will boost both of Clinical Data’s genomics divisions

A double gain: Epidauros acquisition will boost both of Clinical Data’s genomics divisions

Clinical Data Inc. in late August announced that it had acquired privately held Epidauros Biotechnologie AG of Bernried, Germany, in a cash transaction valued at 8.75 million Euros—or approximately $11.84 million.

FDA looks to India

FDA looks to India

GVK Biosciences (GVK Bio) and the U.S. Food and Drug Administration (FDA) signed a material transfer agreement in August under which GVK Bio is granting access to its Clinical Biomarker Database to the FDA.

Operon, DNA2.0 aim for bigger share of synthetic gene market

Operon, DNA2.0 aim for bigger share of synthetic gene market

Under a new partnership, Operon is providing oligonucleotides to DNA2.0 for the synthesis genes to meet the demands of a market the companies say is expected to double annually for the next several years. The co-marketing agreement calls for cross-selling their core products to their respective customer bases.

A startup with a pedigree: Alnylam, Isis launch Regulus

A startup with a pedigree: Alnylam, Isis launch Regulus

Cambridge, Mass.-based Alnylam Pharmaceuticals Inc. and Carlsbad, Calif.-based Isis Pharmaceuticals Inc. have launched Regulus Therapeutics LLC, a joint venture focused on the discovery, development and commercialization of miRNA therapeutics.

Global News

Ophthotech in-licenses pair of aptamers

Ophthotech in-licenses pair of aptamers

In a pair of in-licensing deals with Archemix Corp. and OSI Pharmaceuticals, Ophthotech Corp. recently acquired rights to aptamer compounds for the treatment of macular degeneration. Ophthotech is a new company formed by former executive of Eyetech, which OSI Pharmaceuticals acquired in late 2005.

Bend Research, Pfizer seek to improve drug bioavailability

Bend Research, Pfizer seek to improve drug bioavailability

Bend Research and Pfizer have developed a new delivery technology—-spray-dried dispersions (SDDs)—-that Bend recently announced it will make available to other organizations looking to improve the clinical effectiveness of experimental compounds.

Informatics

Getting real with trials

Getting real with trials

INC Research has partnered with TheraSim, to put together a CPM system that will provide an interactive patient simulation environment designed to both assess and improve the skills and behaviors of clinicians.
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