October 2023- Volume 19, Issue 9
In this Issue
Editor's Focus
Robotic pills deliver gastrointestinal injections
Robotic pills deliver gastrointestinal injections
Researchers developed ingestible capsules that inject drugs into the stomach and small intestine, providing a novel oral delivery method for biologics.
Editors Insight
Scientists, don’t stick to the status quo
Scientists, don’t stick to the status quo
We should expand our definition of what it means to be a scientist to include all of the important roles that stem from this identity.
Human Genetics
Human genetics influence susceptibility to infection
Human genetics influence susceptibility to infection
Scientists identified specific genes that confer protection or vulnerability to various infections, pointing the way to new treatments.
New weapons in the fight against sickle cell disease
New weapons in the fight against sickle cell disease
For decades, treatment options for sickle cell disease have been extremely limited. Soon, gene therapies and a host of pharmaceuticals could alleviate the immense burden of this disease.
Drug Formulation
No more daily pills: A new star in long-acting drug delivery
No more daily pills: A new star in long-acting drug delivery
With a star-shaped drug delivery platform that can stay in the stomach for a week or more, researchers hope to improve medication compliance and overall health.
Safety buttons for CRISPR/Cas9
Safety buttons for CRISPR/Cas9
New technologies keep CRISPR/Cas9 in check and minimize off-target risks.
Microbiology
Lighting up tuberculosis with point-of-care diagnostics
Lighting up tuberculosis with point-of-care diagnostics
Mireille Kamariza develops new chemistry-driven diagnostics for tuberculosis that can reduce the time to treatment from weeks to minutes.
An mRNA twist to the HIV vaccine problem
An mRNA twist to the HIV vaccine problem
For decades, researchers have tried to craft a successful vaccine for HIV. mRNA vaccines may offer the answer.
Bioanalytics
Fishing for safer nanomedicine
Fishing for safer nanomedicine
To pinpoint nanomaterials that show toxic effects in biological systems, researchers rely on the petite but powerful zebrafish.
A squirmy system for studying cancer’s spread
A squirmy system for studying cancer’s spread
Researchers use fluorescence-based imaging to visualize a cellular invasion event in worms, revealing candidates for gene knockdown strategies to block metastasis.
