October 2022 Volume 18, Issue 10

October 2022

Volume 18, Issue 10 | October 2022

October 2022

In this Issue

Editor's Focus

A dejected healthcare worker, wearing a plastic face shield, a facemask, and a gown, sits on the floor leaning against the wall

Preparing for the inevitable next pandemic

In the 21st century, viral spillovers will become more and more common. We are not in the dark and can prepare now for new breakouts before they even begin.

Immunology

An illustrated scientist is surrounded by immune cells and antibodies.

New monoclonal antibody therapeutics made straight from cancer patients’ blood

Some scientists use cancer patients as libraries for discovering novel immunotherapies.
A vibrant, hand drawn image depicts SARS-CoV-2 particles.

Understudied antibodies against SARS-CoV-2 predict patient survival

COVID-19 researchers focus their studies on antibodies targeting exposed parts of SARS-CoV-2, but in a new study, a group of researchers showed that antibodies targeting proteins inside the virus are just as important for a robust immune response.
A Navy officer tilts his head back so a medical professional can insert a small syringe filled with a flu vaccine into his nose.

A universal flu vaccine might not look very universal

New research on vaccines that cover multiple influenza viruses arrives frequently, but biological, evolutionary, and communications challenges remain.

Dermatology

A photograph of a healed, circular scar on a person’s back after a burn.

An extra sticky mussel-inspired skin graft heals without scars

To avoid the pain, scars, and complications of traditional skin grafts and sutures, scientists take inspiration from mussels, some of the stickiest, most resilient animals on Earth.
A drawing of a tattoo machine with tattoo art of leaves coming out of it, and a rose tattoo is drawn next to it.

Tattoo therapeutics deliver medicine more than skin deep

From ancient medicines to equipping humans with new senses, tattoos are more than just permanent marks on the skin. They may boost immune function, and they have the potential to effectively deliver therapeutics through the skin.

CRISPR

An illustration of tweezers removing a piece of a DNA molecule

Science Milestone: The creation of CRISPR

Scientists harnessed the prokaryotic immune system to develop a groundbreaking gene editing technology that improves human health.
Two gloved hands clip a piece of DNA with scissors and pluck a piece of DNA with tweezers, respectively.

CRISPR-edited white adipocytes effectively treat diabetes in mice

Implanting brown fat into mice fed a high fat diet helps them lose weight and become glucose tolerant. Will it do the same for humans?
Samira Kiani walks with a fellow scientist on a road next to a field on the set of her documentary film about genetic technology and the future, “Make People Better.”

Infusing CRISPR therapeutics with safety and soul

Samira Kiani combines her passion for art and design with synthetic biology to create safer CRISPR-based therapeutics for the future.

Drug Manufacturing

Marine sponges are a rich source of unique and biologically active compounds.

A potential therapy for curing HIV comes from the sea

Small molecule drugs that trigger the death of cells storing latent viruses are a promising approach for treating HIV. Researchers identified a potent compound in a marine sponge — a more likely source than it may seem.  
A drawing of scientists in white lab coats examining a spine with a magnifying glass and a picture of a bone on a clipboard.

For local mRNA delivery, nanoparticles stick to the bone

Researchers designed a lipid nanoparticle that sticks to bone minerals, increasing mRNA delivery and therapeutic protein expression in the bone.
A silhouette of the body’s digestive system with pills near the mouth and enzymes in the intestine.

A silk cocoon gives a protective shell to oral drugs in the gut

Researchers are harnessing the power of silk to develop a shelf- and digestive tract-stable enzyme treatment for phenylketonuria.
Subscribe to Newsletter

Subscribe to our eNewsletters

Stay connected with all of the latest from Drug Discovery News.

Subscribe

Sponsored

A black mosquito is shown on pink human skin against a blurred green backdrop.

Discovering deeper insights into malaria research

Malaria continues to drive urgent research worldwide, with new therapies and tools emerging to combat the parasite’s complex lifecycle and global burden.
Three burgundy round and linear conformations of oligonucleotides are shown against a black background.

Accelerating RNA therapeutic testing with liver microphysiological platforms

Researchers can now study oligonucleotide delivery and efficacy in a system that models a real human liver.
A 3D-rendered illustration of a eukaryotic cell highlighting organelles such as the nucleus, endoplasmic reticulum, mitochondria, and cytoskeletal structures in pink and purple tones.

Shining light on the subcellular proteome

Discover how innovative proteomics tools help researchers peer into once inaccessible organelles, allowing for new targets for drug discovery and development.
Drug Discovery News March 2025 Issue
Latest IssueVolume 21 • Issue 1 • March 2025

March 2025

March 2025 Issue

Explore this issue