October 2021- Volume 17, Issue 10
In this Issue
Editor's Focus
Understanding bacteriophages
Understanding bacteriophages
Ultra-microscopic viruses that selectively target and kill bacteria may mitigate antimicrobial resistance.
Editors Insight
The black swan
The black swan
How can scientists bridge the communication gap between themselves and the public?
Microbiology
Antimicrobial resistance: The silent pandemic
Antimicrobial resistance: The silent pandemic
Scientists continue to ring alarm bells about the risks associated with the continued misuse of antimicrobials and advocate for innovative treatments, improved surveillance, and greater public health education.
Targeting gut bacteria to treat autism
Targeting gut bacteria to treat autism
Scientists leverage the gut microbiome-brain connection to develop new treatments for autism spectrum disorders.
E. coli may hold the key to manufacturing hard-to-make drugs
E. coli may hold the key to manufacturing hard-to-make drugs
Scientists combined engineered E. coli with artificial intelligence to produce effective, high-quality protein and antibody-based drugs at a large scale.
Cell Biology
Harnessing cells' own RNA editing tools for new therapeutics
Harnessing cells' own RNA editing tools for new therapeutics
By redirecting cells’ endogenous RNA editing machinery, scientists can correct disease-causing mutations, bringing a new kind of gene therapy to the clinic.
Special report: Live and let die
Special report: Live and let die
Researchers redefine cell death in disease and drug discovery.
Decoding cell behavior and disease with AI and single-cell transcriptomics
Decoding cell behavior and disease with AI and single-cell transcriptomics
Machine learning paired with single-cell analysis helps scientists identify pathways that cause disease and potential therapeutics.
Rare Diseases
CRISPR-based muscular dystrophy therapy
CRISPR-based muscular dystrophy therapy
An engineer turned biology researcher co-founded a bio-pharma start-up with the goal of using CRISPR to reverse the mutation causing the degenerative muscle disorder Duchenne muscular dystrophy.
Infographic: CRISPR editing for treating Duchenne muscular dystrophy
Infographic: CRISPR editing for treating Duchenne muscular dystrophy
Researchers are using CRISPR gene editing to restore function of the mutant protein that causes Duchenne muscular dystrophy, a genetic disease that causes muscle degeneration.
Genetic studies of rare undiagnosed diseases take flight with model organisms
Genetic studies of rare undiagnosed diseases take flight with model organisms
Researchers use fruit flies to figure out how genetic mutations disrupt biology and how drugs might reverse these effects.
