October 2021 Volume 17, Issue 10

October 2021 Issue, Drug Discovery News

Volume 17, Issue 10 | October 2021

October 2021

In this Issue

Microbiology

EHEC grown on an agar plate.

E. coli may hold the key to manufacturing hard-to-make drugs

Scientists combined engineered E. coli with artificial intelligence to produce effective, high-quality protein and antibody-based drugs at a large scale.
child in orange shirt is looking out a window

Targeting gut bacteria to treat autism

Scientists leverage the gut microbiome-brain connection to develop new treatments for autism spectrum disorders.
Veterinarian with syringe ready to give vaccine shot to pigs at cattle farm

Antimicrobial resistance: The silent pandemic

Scientists continue to ring alarm bells about the risks associated with the continued misuse of antimicrobials and advocate for innovative treatments, improved surveillance, and greater public health education.

Rare Diseases

ACOX1-driven neurodegeneration is one of the diseases that Bellen’s team has modeled in flies to find drug treatments. In a fly without ACOX1, the immune system attacks the fly’s own tissue.

Genetic studies of rare undiagnosed diseases take flight with model organisms

Researchers use fruit flies to figure out how genetic mutations disrupt biology and how drugs might reverse these effects.
Disabled boy in wheelchair holding mother's hand on path

CRISPR-based muscular dystrophy therapy

An engineer turned biology researcher co-founded a bio-pharma start-up with the goal of using CRISPR to reverse the mutation causing the degenerative muscle disorder Duchenne muscular dystrophy.
Dystrophied muscle

Infographic: CRISPR editing for treating Duchenne muscular dystrophy

Researchers are using CRISPR gene editing to restore function of the mutant protein that causes Duchenne muscular dystrophy, a genetic disease that causes muscle degeneration.

Cell Biology

Big Data futuristic background

Decoding cell behavior and disease with AI and single-cell transcriptomics

Machine learning paired with single-cell analysis helps scientists identify pathways that cause disease and potential therapeutics.
Genetic engineering

Harnessing cells' own RNA editing tools for new therapeutics 

By redirecting cells’ endogenous RNA editing machinery, scientists can correct disease-causing mutations, bringing a new kind of gene therapy to the clinic.
Grim Reaper

Special report: Live and let die

Researchers redefine cell death in disease and drug discovery.

Editors Insight

Black swan

The black swan

How can scientists bridge the communication gap between themselves and the public?
Subscribe to Newsletter

Subscribe to our eNewsletters

Stay connected with all of the latest from Drug Discovery News.

Subscribe

Sponsored

An illustration of the tumor microenvironment, showing cancer cells, T cells, and nanoparticles interacting within a complex biological system

A closer look at the tumor microenvironment 

New technologies are allowing researchers to delve deeper into the complex tumor landscape.
An image of a western blot transfer showing the white, square transfer membrane with orange and blue bands representing the protein molecules undergoing transfer on a black and white machine.

Exploring stain-free western blotting

Researchers can achieve seamless western blot experiments by implementing advancements in stain-free technology, normalization methods, and compliance integration. 
A digital representation of a DNA double helix surrounded by molecular structures and chemical formulas.

Streamlining biopharmaceutical analysis with digital solutions

Discover how digitization improves data integrity and accelerates decision-making in biotherapeutics development. 
Drug Discovery News November 2024 Issue
Latest IssueVolume 20 • Issue 6 • November 2024

November 2024

November 2024 Issue

Explore this issue