October 2017- Volume 13, Issue 10
In this Issue
Preclinical
At the forefront of fibrosis
At the forefront of fibrosis
Preclinical data for MRG-201 in pulmonary fibrosis reported by miRagen
It’s all in the presentation
It’s all in the presentation
A quick roundup of some recent preclinical data presentations
Nano vs. flu
Nano vs. flu
Novavax’ preclinical influenza nanoparticle vaccine shows promise, study says
Attacking asthma
Attacking asthma
Second preclinical study with MSCs shows positive results
Contract Services
Advancing preclinical research
Advancing preclinical research
CrownBio launches innovative inflammatory disease models
East Coast meets Far East
East Coast meets Far East
PAREXEL and Osaka International Cancer Institute ally for clinical research
Expanding universe
Expanding universe
Four contract service providers make moves to grow
PharmaLex enters into strategic partnership with Volv Global
PharmaLex enters into strategic partnership with Volv Global
New collaboration will use innovative AI technology to support PharmaLex’s pharmacovigilance solutions
Discovery
Strep sit-rep
Strep sit-rep
M protein sets off white blood cells’ early-warning system
Extending an oncology effort
Extending an oncology effort
Cancer Research UK and Newcastle University extend discovery alliance with Astex
Inventiva and AbbVie extend agreement
Inventiva and AbbVie extend agreement
Companies will continue to collaborate on discovery of new RORγ inverse agonist drug candidates
Back on the beat
Back on the beat
NIH awards grant to Numerate to identify antiarrhythmic drug candidates
Diagnostics
Keeping it simple
Keeping it simple
Clinical Genomics and QIAGEN partner on liquid biopsies to diagnose recurrence of colorectal cancer
Enterome and Nestlé Health Science launch into diagnostics
Enterome and Nestlé Health Science launch into diagnostics
Companies create Microbiome Diagnostics Partners with eye on IBF, liver disease and more
Sequencing all chromosomes to identify rare disease
Sequencing all chromosomes to identify rare disease
Study from NIH and other institutions may help improve prenatal genetic screening
A test for chronic fatigue; a boon for Hemispherx
A test for chronic fatigue; a boon for Hemispherx
Stanford University study may lead to chronic fatigue syndrome diagnostic test
Business & Government Policy
Imaging inflection
Imaging inflection
Invicro acquires Imanova, expanding global imaging capabilities
On the cutting edge
On the cutting edge
A roundup of instrumentation, software and other tools and technology news
Comments published on bids to host EMA
Comments published on bids to host EMA
Staff retention and accessibility for delegates and experts key to ensure agency’s ability to function
BARDA in the news
BARDA in the news
U.S. agency awards contracts to Achaogen and Emergent BioSolutions
A sky-high price tag for Kite
A sky-high price tag for Kite
Gilead secures Kite Pharma for $11.9B in second-largest deal of 2017
Research & Development
Modeling the lung-liver connection
Modeling the lung-liver connection
Multi-organ-on-a-chip model promises wide-ranging applications
Algorithm for addiction
Algorithm for addiction
Prescient Medicine’s new genetic test aims to predict future opioid addicts
Time for a ‘brain dump’
Time for a ‘brain dump’
Rounding up some recent neurological R&D stories
Shedding some light on the subject
Shedding some light on the subject
Researchers use fluorescent sensors to elucidate GTP activity in cells
Clinical Trials
Two trials with heart
Two trials with heart
Repatha shows its stuff in FOURIER and GLACOV trials
Galapagos FLORA trial targets IPF
Galapagos FLORA trial targets IPF
Autotaxin is increasingly seen as a player in the pulmonary disease
BioCryst gears up for Phase 3
BioCryst gears up for Phase 3
Promising Phase 2 results in HAE point to efficacy, ideal dose level
A tour of trial tech
A tour of trial tech
Giving you a quick peek at some of the tools and technology news recently in clinical trials
Migraine management
Migraine management
Erenumab could spell relief for chronic migraine sufferers
Commentary
Guest Commentary: Should you be concerned about temporary data?
Guest Commentary: Should you be concerned about temporary data?
As regulatory agencies evolve their thinking around data integrity mandates, the guidance is pointing to curbing the ability to alter data in temporary memory before it becomes permanent
The people vs. pharma
The people vs. pharma
We seem to have lost the ability to get along, and this is evident in the relationship between the life sciences and the larger society, among other places
Editor's Focus
Dear readers, it’s time to meet Pete (if you haven’t already)
Dear readers, it’s time to meet Pete (if you haven’t already)
Introducing you to one of our long-running columnists here at DDNews, Peter T. Kissinger, so that you know what kind of person you're dealing with...and what kind of experience and understanding, too, that he brings
Feature
Show Preview for Neuroscience 2017: A mind-trip in D.C.
Show Preview for Neuroscience 2017: A mind-trip in D.C.
SfN marches on Washington (figuratively speaking) to expand neuroscience knowledge and networking
Special Reports
Special Focus on Cancer Research News: In the pink with oncology R&D
Special Focus on Cancer Research News: In the pink with oncology R&D
A roundup of recent research and clinical work within the realm of breast cancer, as well as substantial coverage of immuno-oncology and other cancer areas
