October 2017 Volume 13, Issue 10

Volume 13, Issue 10 | October 2017

October 2017

In this Issue

Commentary

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Guest Commentary: Should you be concerned about temporary data?

As regulatory agencies evolve their thinking around data integrity mandates, the guidance is pointing to curbing the ability to alter data in temporary memory before it becomes permanent
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The people vs. pharma

We seem to have lost the ability to get along, and this is evident in the relationship between the life sciences and the larger society, among other places

Editor's Focus

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Dear readers, it’s time to meet Pete (if you haven’t already)

Introducing you to one of our long-running columnists here at DDNews, Peter T. Kissinger, so that you know what kind of person you're dealing with...and what kind of experience and understanding, too, that he brings

Feature

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Show Preview for Neuroscience 2017: A mind-trip in D.C.

SfN marches on Washington (figuratively speaking) to expand neuroscience knowledge and networking

Special Reports

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Special Focus on Cancer Research News: In the pink with oncology R&D

A roundup of recent research and clinical work within the realm of breast cancer, as well as substantial coverage of immuno-oncology and other cancer areas

Discovery

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Back on the beat

NIH awards grant to Numerate to identify antiarrhythmic drug candidates
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Strep sit-rep

M protein sets off white blood cells’ early-warning system
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Extending an oncology effort

Cancer Research UK and Newcastle University extend discovery alliance with Astex
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Inventiva and AbbVie extend agreement

Companies will continue to collaborate on discovery of new RORγ inverse agonist drug candidates

Clinical Trials

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Migraine management

Erenumab could spell relief for chronic migraine sufferers
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Two trials with heart

Repatha shows its stuff in FOURIER and GLACOV trials
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Galapagos FLORA trial targets IPF

Autotaxin is increasingly seen as a player in the pulmonary disease
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BioCryst gears up for Phase 3

Promising Phase 2 results in HAE point to efficacy, ideal dose level
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A tour of trial tech

Giving you a quick peek at some of the tools and technology news recently in clinical trials

Business & Government Policy

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A sky-high price tag for Kite

Gilead secures Kite Pharma for $11.9B in second-largest deal of 2017
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Imaging inflection

Invicro acquires Imanova, expanding global imaging capabilities
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On the cutting edge

A roundup of instrumentation, software and other tools and technology news
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Comments published on bids to host EMA

Staff retention and accessibility for delegates and experts key to ensure agency’s ability to function
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BARDA in the news

U.S. agency awards contracts to Achaogen and Emergent BioSolutions

Diagnostics

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A test for chronic fatigue; a boon for Hemispherx

Stanford University study may lead to chronic fatigue syndrome diagnostic test
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Keeping it simple

Clinical Genomics and QIAGEN partner on liquid biopsies to diagnose recurrence of colorectal cancer
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Enterome and Nestlé Health Science launch into diagnostics

Companies create Microbiome Diagnostics Partners with eye on IBF, liver disease and more
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Sequencing all chromosomes to identify rare disease

Study from NIH and other institutions may help improve prenatal genetic screening

Research & Development

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Modeling the lung-liver connection

Multi-organ-on-a-chip model promises wide-ranging applications
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Algorithm for addiction

Prescient Medicine’s new genetic test aims to predict future opioid addicts
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Time for a ‘brain dump’

Rounding up some recent neurological R&D stories
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Shedding some light on the subject

Researchers use fluorescent sensors to elucidate GTP activity in cells

Preclinical

Nano vs. flu

Novavax’ preclinical influenza nanoparticle vaccine shows promise, study says
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Attacking asthma

Second preclinical study with MSCs shows positive results
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At the forefront of fibrosis

Preclinical data for MRG-201 in pulmonary fibrosis reported by miRagen
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It’s all in the presentation

A quick roundup of some recent preclinical data presentations

Contract Services

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Advancing preclinical research

CrownBio launches innovative inflammatory disease models
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East Coast meets Far East

PAREXEL and Osaka International Cancer Institute ally for clinical research
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Expanding universe

Four contract service providers make moves to grow
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PharmaLex enters into strategic partnership with Volv Global

New collaboration will use innovative AI technology to support PharmaLex’s pharmacovigilance solutions
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Driving gene therapy with nonviral vectors 

Learn why nonviral vectors are on the rise in gene therapy development.
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Milestone: Leapfrogging to quantitative, high throughput protein detection and analysis

Researchers continuously push the boundaries of what’s possible with protein analysis tools.
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Advancing immuno-oncology research with cellular assays

Explore critical insights into immunogenicity and immunotoxicity assays for cancer therapies.
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