October 2017- Volume 13, Issue 10

In this Issue

Contract Services

Expanding universe

Expanding universe

Four contract service providers make moves to grow

PharmaLex enters into strategic partnership with Volv Global

PharmaLex enters into strategic partnership with Volv Global

New collaboration will use innovative AI technology to support PharmaLex’s pharmacovigilance solutions

Advancing preclinical research

Advancing preclinical research

CrownBio launches innovative inflammatory disease models

East Coast meets Far East

East Coast meets Far East

PAREXEL and Osaka International Cancer Institute ally for clinical research

Discovery

Strep sit-rep

Strep sit-rep

M protein sets off white blood cells’ early-warning system

Extending an oncology effort

Extending an oncology effort

Cancer Research UK and Newcastle University extend discovery alliance with Astex

Inventiva and AbbVie extend agreement

Inventiva and AbbVie extend agreement

Companies will continue to collaborate on discovery of new RORγ inverse agonist drug candidates

Back on the beat

Back on the beat

NIH awards grant to Numerate to identify antiarrhythmic drug candidates

Preclinical

Nano vs. flu

Nano vs. flu

Nano vs. flu

Novavax’ preclinical influenza nanoparticle vaccine shows promise, study says

Attacking asthma

Attacking asthma

Second preclinical study with MSCs shows positive results

At the forefront of fibrosis

At the forefront of fibrosis

Preclinical data for MRG-201 in pulmonary fibrosis reported by miRagen

It’s all in the presentation

It’s all in the presentation

A quick roundup of some recent preclinical data presentations

Business & Government Policy

On the cutting edge

On the cutting edge

A roundup of instrumentation, software and other tools and technology news

Comments published on bids to host EMA

Comments published on bids to host EMA

Staff retention and accessibility for delegates and experts key to ensure agency’s ability to function

BARDA in the news

BARDA in the news

U.S. agency awards contracts to Achaogen and Emergent BioSolutions

Imaging inflection

Imaging inflection

Invicro acquires Imanova, expanding global imaging capabilities

A sky-high price tag for Kite

A sky-high price tag for Kite

Gilead secures Kite Pharma for $11.9B in second-largest deal of 2017

Research & Development

Modeling the lung-liver connection

Modeling the lung-liver connection

Multi-organ-on-a-chip model promises wide-ranging applications

Algorithm for addiction

Algorithm for addiction

Prescient Medicine’s new genetic test aims to predict future opioid addicts

Time for a ‘brain dump’

Time for a ‘brain dump’

Rounding up some recent neurological R&D stories

Shedding some light on the subject

Shedding some light on the subject

Researchers use fluorescent sensors to elucidate GTP activity in cells

Clinical Trials

Two trials with heart

Two trials with heart

Repatha shows its stuff in FOURIER and GLACOV trials

Galapagos FLORA trial targets IPF

Galapagos FLORA trial targets IPF

Autotaxin is increasingly seen as a player in the pulmonary disease

BioCryst gears up for Phase 3

BioCryst gears up for Phase 3

Promising Phase 2 results in HAE point to efficacy, ideal dose level

A tour of trial tech

A tour of trial tech

Giving you a quick peek at some of the tools and technology news recently in clinical trials

Migraine management

Migraine management

Erenumab could spell relief for chronic migraine sufferers

Diagnostics

A test for chronic fatigue; a boon for Hemispherx

A test for chronic fatigue; a boon for Hemispherx

Stanford University study may lead to chronic fatigue syndrome diagnostic test

Keeping it simple

Keeping it simple

Clinical Genomics and QIAGEN partner on liquid biopsies to diagnose recurrence of colorectal cancer

Enterome and Nestlé Health Science launch into diagnostics

Enterome and Nestlé Health Science launch into diagnostics

Companies create Microbiome Diagnostics Partners with eye on IBF, liver disease and more

Sequencing all chromosomes to identify rare disease

Sequencing all chromosomes to identify rare disease

Study from NIH and other institutions may help improve prenatal genetic screening

Commentary

The people vs. pharma

The people vs. pharma

We seem to have lost the ability to get along, and this is evident in the relationship between the life sciences and the larger society, among other places

Guest Commentary: Should you be concerned about temporary data?

Guest Commentary: Should you be concerned about temporary data?

As regulatory agencies evolve their thinking around data integrity mandates, the guidance is pointing to curbing the ability to alter data in temporary memory before it becomes permanent

Editor's Focus

Dear readers, it’s time to meet Pete (if you haven’t already)

Dear readers, it’s time to meet Pete (if you haven’t already)

Introducing you to one of our long-running columnists here at DDNews, Peter T. Kissinger, so that you know what kind of person you're dealing with...and what kind of experience and understanding, too, that he brings

Feature

Show Preview for Neuroscience 2017: A mind-trip in D.C.

Show Preview for Neuroscience 2017: A mind-trip in D.C.

SfN marches on Washington (figuratively speaking) to expand neuroscience knowledge and networking

Special Reports

Special Focus on Cancer Research News: In the pink with oncology R&D

Special Focus on Cancer Research News: In the pink with oncology R&D

A roundup of recent research and clinical work within the realm of breast cancer, as well as substantial coverage of immuno-oncology and other cancer areas
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