October 2011 Volume 7, Issue 10

Volume 7, Issue 10 | October 2011

October 2011

In this Issue

Global News

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Taking aim at Alzheimer’s

Evotec, Roche to partner on development of Alzheimer’s treatment
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An affinity for Graffinity

NovAliX and Galapagos collaborate in osteoarthritis discovery research program
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Small but mighty

Ascenta Therapeutics licenses experimental small-molecule cancer drug candidate to Debiopharm
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Lilliputian meets Brobdingnagian

Astellas Pharma signs a license agreement with Evec for a fully human antibody
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U.K. union has great chemistry

Cresset, Redx Pharma to collaborate on drug discovery for a wide range of therapeutic areas

Instruments & Informatics

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Looking beyond imaging and detection

PerkinElmer acquires Caliper Life Sciences for approximately $600 million, with eye toward expansion into preclinical work and companion Dx
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Going with the flow

EMD Millipore acquires cell-imaging instrument maker Amnis
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Broadway boogie-woogie

NuGEN will partner with Advanced Liquid Logic to co-develop Mondrian-like microfluidic sample preparation automation
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On a kidney quest

Critical Path Institute’s collaboration with Pharsight explores new model in battle against kidney disease
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Sweet deal for Agilent in Asia

Agilent Technologies and Chungnam National University team up to push glycomics research forward
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Aridhia, Glencoe Software create data analysis products

Aridhia Informatics Ltd., a multidisciplinary health informatics company, recently partnered with Glencoe Software to create products to aid the development of personalized therapies and deliver improved patient outcomes.

Research & Development

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Digging in the dirt

Researchers at the universities of Nottingham and Maastricht make headway in the use of the bacteria strain Clostridia as a way to safely and effectively deliver drugs to tumor sites
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Acquisition is par for the course

Par Pharmaceutical acquires rival Anchen Pharmaceuticals for $410 million
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Stem cell breakthroughs within Cyte?

BioTime’s ReCyte and OncoCyte subsidiaries ink pact with Cornell on vascular cells derived from hESCs
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Stem cells offer new hope for MS patients

Cleveland-based research team use the mesenchymal stem cells of MS patients to treat the debilitating disease
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Specificity counts in Merck deal

Zymeworks Inc. to collaborate with Merck on developing bi-specific antibody Therapeutics

Omics & Systems Biology

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PTH at picograms

Thermo Fisher Scientific acquires Intrinsic Bioprobes to enhance workflow for biomarker research and diagnostics
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Lessons in lifestyle and lipids

Shimadzu and the University of Tokyo to develop lipidomics technology for biomarker discovery
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On the hunt for genetic clues

HudsonAlpha Institute, U of Michigan search for genetic links to bipolar disorder
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Not just an expression

Clavis, Skyline team up on biomarkers for AML drug
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Think about the orphans

Synageva BioPharma enters R&D partnership with Mitsubishi Tanabe Pharma to develop protein therapeutic for orphan disease target

Diagnostics

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Billion-dollar boost

GE's health business unit earmarks $1 billion for cancer diagnostics and molecular imaging
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Queue up with QIAGEN

QIAGEN announces companion Dx partnerships with Pfizer, Lilly
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Colorectal cancer compatriots

Arizona State and China's Sun Yat-sen University to develop early diagnostics against colorectal cancer
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Together again against prostate cancer

Genomatix and Uniformed Service University build on previous work to seek prognostic genetic markers through next-gen sequencing
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Irish blessing

Queen\'s University of Belfast and Almac agree to work on cancer tests
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TrovaGene licenses Hairy Cell Leukemia assay

TrovaGene Inc., a developer of transrenal molecular diagnostics to facilitate personalized medicine, has signed a worldwide exclusive license for an assay that detects Hairy Cell Leukemia (HCL).

Commentary

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Multi-parameter optimization: The delicate balancing act of drug discovery

Dealing with complex, multi-parameter data with high uncertainty is an enormous challenge. One must consider the overall balance of properties as early as possible in the process to focus on chemistries with the best chance of quick progress and downstream success.
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Taxes, innovation and life science jobs

It's time to stop defining the problem and start defining solutions.

Editor's Focus

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Announcing the ddn Cancer Research Portal: Your gateway to the latest oncology news, trends and resources

Cancer research dominates nearly every section of our newspaper and other news vehicles. That’s why we decided to launch our latest news division, the ddn Cancer Research Portal, your gateway to the latest oncology news, trends and resources.

Contract Services

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Building on a strong foundation

ICON selected as a preferred provider for early-phase clinical development by Bristol-Myers Squibb
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Blueprint for neurotherapeutics

AMRI wins five-year, $43 million federal contract award
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Build it and they will come

Start-up research institute forms strategic alliance with LabCorp Clinical Trials to offer specialized biomarker and assay development services
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Advantar partners with DavosPharma

Companies collaborating to broaden service offerings for U.S. clients

Feature

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The big brains

Society for Neuroscience brings a wide range of perspectives to the nation's capital with Neuroscience 2011
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Blue and red plate specials

Regardless of where you lie on the political or ideological spectrum, D.C. offers plenty of culinary choices
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Such sights to see

You know about the Washington Monument, Lincoln Memorial and the rest, but here are some lesser-hyped places
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