November 2024 Volume 20, Issue 6

Volume 20, Issue 6 | November 2024
November 2024
In this Issue
Stem Cells

A protein that makes pancreatic stem cells invisible
Researchers showed that pancreatic cancer stem cells produce a protein usually made by neutrophils to evade the immune system and keep growing.Hematology

On the cusp of a CAR T cell cure for lupus
Exhilarated but cautious, researchers are eager to see if CAR T cell therapy offers a one-time treatment for lupus.
Old drugs shed new light on a rare skin disease
Drug repurposing trials for ichthyosis reveal complexity in the long-untreated disease.
Targeting a clotting protein to treat neonatal brain bleeds
Researchers discovered that a blood clotting protein, fibrinogen, harms brain development during bleeds in preterm infants.Diagnostics

Detecting Parkinson’s disease earlier could prevent brain damage
Scores of neurons are already dead by the time Parkinson’s disease is usually diagnosed. Scientists aim to identify patients earlier and intervene before it’s too late.
Playing tug-of-war with platelets
With new tools, researchers hope to improve diagnosis of platelet dysfunction by measuring their forces.
The metabolites that define a bad night’s sleep
The link between metabolism and sleep is helping scientists find new biomarkers to detect sleepless nights and diagnose chronic sleep disorders.Stem Cells

Rejuvenating lung stem cells for idiopathic pulmonary fibrosis
Michael Bollong and his team discovered a way to restore lung stem cells’ regenerative capacity and a potential drug for idiopathic pulmonary fibrosis.Editor's Focus

Milestone: The history of bone marrow transplantation
In a journey fraught with heartache and persistence, medical research giants paved the way for successful bone marrow transplantation.
Explained: What is mesenchymal stem cell therapy?
Born to differentiate and heal, mesenchymal stem cells carry great potential for treating a wide spectrum of diseases.Editors Insight

Rediscovering forgotten drugs with new AI tools
As scientific output grows, the risk of a promising drug getting lost increases, but advances in artificial intelligence and machine learning may prevent that.Gene Therapy

Targeting Rett syndrome at the source
Rett syndrome currently has no cure. Now, innovations in gene therapy bring the possibility of treating the root cause of the disease closer than ever before.
Gene therapy could treat Alzheimer’s disease
New gene therapies in clinical trials seek to treat Alzheimer’s disease and heal the brain with a dose of helpful genetic material.

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