November 2023 Volume 19, Issue 11

Volume 19, Issue 11 | November 2023
November 2023
In this Issue
Editor's Focus

When happy accidents lead to new discoveries
No one ever hopes to mess up an experiment, but sometimes what seems like a frustrating misstep actually sparks a discovery.
Explained: How do cells migrate?
Cells travel throughout the body, enabling diverse biological phenomena in health and disease.
Hope for prion diseases
From reducing prion protein to fighting neuroinflammation, researchers try different techniques to combat deadly prion diseases.Neuroscience

Tracking the movement of individual proteins in dementia
A dementia-associated tau mutation promotes unusual clustering of Fyn, a protein important for learning and memory.
Musical medicine for Parkinson’s disease
By measuring neural oscillations in the brain, Isabelle Buard studies the effect of music therapy on improving fine motor movements in neurological disorders.
The science of forgetting
Researchers explore the role of forgetting in normal brain function and as a therapeutic target for fear-related disorders.Epigenetics

Deadly alcoholic hepatitis finds hope in epigenetics
With a high mortality rate and no treatment, alcoholic hepatitis is a tragic diagnosis. But a new molecule that alters patient epigenetics may become the first effective therapy for the disease.
Early life adversity leaves marks in the brain
Negative childhood experiences can leave epigenetic scars that haunt organisms for life.
How heritable is the epigenome?
Isabelle Mansuy explores how life experiences alter the epigenome of an organism and its descendants.Tools & Techniques

A new computational tool predicts drug targets and side effects
Scientists developed a way to probe single cell transcriptomic data to find drugs that target cells of interest and to identify cells targeted by specific drugs.

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