November 2023- Volume 19, Issue 11
In this Issue
Editor's Focus
Hope for prion diseases
Hope for prion diseases
From reducing prion protein to fighting neuroinflammation, researchers try different techniques to combat deadly prion diseases.
Explained: How do cells migrate?
Explained: How do cells migrate?
Cells travel throughout the body, enabling diverse biological phenomena in health and disease.
When happy accidents lead to new discoveries
When happy accidents lead to new discoveries
No one ever hopes to mess up an experiment, but sometimes what seems like a frustrating misstep actually sparks a discovery.
Neuroscience
The science of forgetting
The science of forgetting
Researchers explore the role of forgetting in normal brain function and as a therapeutic target for fear-related disorders.
Musical medicine for Parkinson’s disease
Musical medicine for Parkinson’s disease
By measuring neural oscillations in the brain, Isabelle Buard studies the effect of music therapy on improving fine motor movements in neurological disorders.
Tracking the movement of individual proteins in dementia
Tracking the movement of individual proteins in dementia
A dementia-associated tau mutation promotes unusual clustering of Fyn, a protein important for learning and memory.
Epigenetics
Early life adversity leaves marks in the brain
Early life adversity leaves marks in the brain
Negative childhood experiences can leave epigenetic scars that haunt organisms for life.
How heritable is the epigenome?
How heritable is the epigenome?
Isabelle Mansuy explores how life experiences alter the epigenome of an organism and its descendants.
Deadly alcoholic hepatitis finds hope in epigenetics
Deadly alcoholic hepatitis finds hope in epigenetics
With a high mortality rate and no treatment, alcoholic hepatitis is a tragic diagnosis. But a new molecule that alters patient epigenetics may become the first effective therapy for the disease.
Tools & Techniques
A new computational tool predicts drug targets and side effects
A new computational tool predicts drug targets and side effects
Scientists developed a way to probe single cell transcriptomic data to find drugs that target cells of interest and to identify cells targeted by specific drugs.
