Before its COVID-19 era hype, ivermectin was already a wonder drug for parasitic infections. Its renewed interest underscores the need for effective COVID-19 treatments and communication on proper research study design and analysis.
Targeting oncogenic transcription factors like MYC is challenging, but researchers found a way to target its regulator, WDR5, for degradation, exemplifying the capacity of protein degraders to target the “undruggable.”
People metabolize drugs differently, changing the effectiveness and toxicity of drugs between individuals. Genetic testing to identify mutations in metabolic genes that may affect how someone processes a drug is an important step towards precision medicine that is becoming more common in the clinic.
Philip Yeske was an organic chemist for more than 20 years, but when his daughter died from the rare mitochondrial disorder Leigh Syndrome, he turned to connecting researchers, patients, and law makers to speed the discovery of treatments.
Pregnant people with mental health disorders such as depression or bipolar disorder often face an impossible decision: risk their health or their future child's health by discontinuing or continuing their medication.