November 2011- Volume 7, Issue 11

November 2011

In this Issue

Omics & Systems Biology

Nigel's new ark

Nigel's new ark

Ex-ARK Therapeutics CEO launches FKD Therapies to develop and commercialize Merck's gene therapy portfolio

One-stop shopping for microbial genomes

One-stop shopping for microbial genomes

Eurofins MWG Operon and Integrated Genomics to cooperate on end-to-end genomics projects

Of mice and men

Of mice and men

Chromosome-engineered mice lead researchers at Cold Spring Harbor Lab closer to finding the genetic flaws that cause autism

Split-focus

Split-focus

RXi Pharmaceuticals aims to strengthen strategic focus through separation into two distinct publicly traded companies

BMS sees ambiance with Ambrx

BMS sees ambiance with Ambrx

New collaboration to develop biologics for diabetes, heart failure

Research & Development

Puma roars with Pfizer licensing deal

Puma roars with Pfizer licensing deal

Experimental drug shows promise in treating some breast cancer patients

Adding a jewel to the crown

Adding a jewel to the crown

Crown Bioscience acquires IIBR, gaining access to non-human primate models with naturally occurring diabetes and metabolic syndrome

Taking down a triple threat with Karmanos and Komen

Taking down a triple threat with Karmanos and Komen

Karmanos Cancer Institute scores $3.5 million Komen Promise grant for breast cancer research

Vanderbilt forges path for academia

Vanderbilt forges path for academia

University licenses compounds showing promise for Parkinson’s disease, schizophrenia and Fragile X syndrome

Stem cells get specific

Stem cells get specific

Scientists at New York Stem Cell Foundation make advance in development of patient-specific stem cells

Feature

A mile-high view

A mile-high view

ASCB annual meeting in Denver will take in high-level views as well as drill deep into cell biology

Art and nature at high altitude

Art and nature at high altitude

In and near Denver lies plenty of beauty, both natural and human-created

Special Reports

Trends in Cell Biology: ddn Interview with Dr. V. Jo Davisson

Trends in Cell Biology: ddn Interview with Dr. V. Jo Davisson

Expert in the cell biology field identifies some of the themes dominating this growing research area

Diagnostics

Hope for the ‘Worried Man Blues’

Hope for the ‘Worried Man Blues’

Study yields potential biomarker for Huntington’s disease activity and drug response

Making an overseas connection

Making an overseas connection

Bioo Scientific and Jungwoo F&B to collaborate to improve cancer diagnosis and treatment

Exonhit, Pfizer collaborate on Alzheimer’s biomarkers

Exonhit, Pfizer collaborate on Alzheimer’s biomarkers

Early-stage collaboration will focus on identifying biomarkers and disease progression

Quantum Materials and Nanoaxis announce tech alliance

Quantum Materials and Nanoaxis announce tech alliance

Companies seek to use biocompatible quantum dots to enable industrial-scale production of nanomedicines

Sony tunes in to microfluidics

Sony tunes in to microfluidics

Electronics powerhouse acquires diagnostic equipment provider Micronics

Instruments & Informatics

Some trick pony

Some trick pony

Bio-Rad acquires QuantaLife’s new award-winning digital PCR technology

Removing a pain point

Removing a pain point

MUSA and Molecular Devices team up, seeking to complement SoftMax Pro functionality with LabSpeed LS

Mapping the Scottish genome

Mapping the Scottish genome

Generation Scotland and Arrayjet collaborate on the development of new products and services for biomarker identification and development

Seeking a silver lining

Seeking a silver lining

Golden Helix, Expression Analysis work together on RNA sequencing

Back to school

Back to school

Absorption Systems initiates collaboration with academic researchers to develop improved in-vitro pharmacokinetic predictions

Commentary

The biorepository: The cornerstone of drug development

The biorepository: The cornerstone of drug development

Now is the time for pharmaceutical and biotech companies, both large and small, to assess their current sample management strategies to ensure current and future drug discovery is not jeopardized by sub-optimal management processes or samples or lack of sample data.

Patent News

In the EU, stem cells unpatentable if an embryo is destroyed

In the EU, stem cells unpatentable if an embryo is destroyed

In late October, the Court of Justice of the European Union (CJEU) issued a judgment in the case of Brüstle v. Greenpeace, banning the issuance of patents for stem cells on ethical grounds.

Editor's Focus

A news story is only as good as its sources

A news story is only as good as its sources

Throughout the long and complicated journey of Sherley v. Sebelius through the courts thus far, our coverage has been marked by rare and gracious access to the plaintiffs in the case.

Government Watch

Signed, sealed and delivered

Signed, sealed and delivered

Patent reform now law in United States

Prometheus—unbound or not

Prometheus—unbound or not

U.S. Supreme Court to decide validity of company’s patent under challenge by Mayo Collaborative Services

FDA, federal agencies team up to develop technologies that predict drug safety

FDA, federal agencies team up to develop technologies that predict drug safety

On Sept. 19, President Barack Obama announced that the U.S. National Institutes of Health (NIH) will collaborate with the U.S. Food and Drug Administration (FDA) and the Defense Advanced Research Projects Agency (DARPA) to develop cutting-edge technologies to predict drug safety.

If at first you don’t succeed …

If at first you don’t succeed …

Plaintiffs in Sherley stem cell case appeal dismissal

Global News

MS and NSCLC targeted

MS and NSCLC targeted

Merck Serono and Ono Pharmaceutical to develop oral multiple sclerosis drug and cancer immunotherapy

Going after glycobiology

Going after glycobiology

GE Healthcare teams up with Ireland’s NIBRT to drive new technologies for the development of therapeutic antibodies

Catching the pipeline

Catching the pipeline

Biotie snares Newron CNS pipeline in deal worth up to $63 million

Serving up with Servier

Serving up with Servier

New alliance with Galapagos to feature targets from both companies

Looking for a TD on TB

Looking for a TD on TB

CDRI, NITD team up for a tuberculosis cure
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