May 2024- Volume 20, Issue 3

In this Issue

Editors Insight

Two profile outlines of humans with scientific and artistic images overlaid

Science needs creativity

Science needs creativity

The pursuit of scientific knowledge relies on analytical thinking, but creativity also plays an essential role.

Aging

Five cartoon vials of blood with a doctor holding a magnifying glass to one

Young blood reverses aging in old organs

Young blood reverses aging in old organs

Young blood rejuvenates aging organs in rodents. Researchers are studying the potential to use young blood-based treatments in aging humans too.
A close-up of a scientist’s hands in black gloves holding an obscured object under a microscope.

Reproductive aging leads to many women’s health problems

Reproductive aging leads to many women’s health problems

Slowing female reproductive aging could be the key to improving women’s health.

RNA

A microscopic view of white, orange, and green molecules

Silencing genes to prevent disease with RNAi drugs

Silencing genes to prevent disease with RNAi drugs

Alnylam Pharmaceuticals develops therapeutics based on the RNA interference (RNAi) pathway discovered in 1998.
A 3D rendering of a yellow lipid nanoparticle holding an mRNA therapeutic is shown entering a pink human cell.

Moderna’s path to mRNA therapies for rare metabolic disorders

Moderna’s path to mRNA therapies for rare metabolic disorders

Paolo Martini leads the biotech company’s rare disease research program with the hope of developing the very first treatments for genetic metabolic disorders.

Protein Drugs

White bowls with brown circular objects on a brown wooden background

A new Goldilocks drug class: macrocyclic peptides

A new Goldilocks drug class: macrocyclic peptides

By making peptides ring shaped, researchers uncovered a new class of drugs that is “just right” for previously undruggable targets.

Cell Therapy

Two Antion Biosciences researchers look at a fluorescent image on a computer monitor while wearing white lab coats and purple gloves.

Silencing cancer with CAR T cells

Silencing cancer with CAR T cells

A new approach to cell engineering could make off-the-shelf CAR T cell therapies a reality.
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DDN Magazine May 2024

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• Volume 20 • Issue 3 • May 2024

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