May 2024 Volume 20, Issue 3

Volume 20, Issue 3 | May 2024
May 2024
In this Issue
Aging

Reproductive aging leads to many women’s health problems
Slowing female reproductive aging could be the key to improving women’s health.
Explained: At what age does the immune system weaken?
After decades of combating daily assaults, the immune system undergoes dramatic changes that drastically affect human health.
Young blood reverses aging in old organs
Young blood rejuvenates aging organs in rodents. Researchers are studying the potential to use young blood-based treatments in aging humans too.RNA

Moderna’s path to mRNA therapies for rare metabolic disorders
Paolo Martini leads the biotech company’s rare disease research program with the hope of developing the very first treatments for genetic metabolic disorders.
Silencing genes to prevent disease with RNAi drugs
Alnylam Pharmaceuticals develops therapeutics based on the RNA interference (RNAi) pathway discovered in 1998.Editors Insight

Science needs creativity
The pursuit of scientific knowledge relies on analytical thinking, but creativity also plays an essential role.Editor's Focus

A new Goldilocks drug class: macrocyclic peptides
By making peptides ring shaped, researchers uncovered a new class of drugs that is “just right” for previously undruggable targets.Cell Therapy

Silencing cancer with CAR T cells
A new approach to cell engineering could make off-the-shelf CAR T cell therapies a reality.
The robots making cell therapies
Scientists and engineers teamed up to use robots to streamline cell therapy manufacturing, aiming to give more patients access to these lifesaving therapies.Protein Drugs

Targeting disease proteins with molecular matchmakers
Many diseases cause proteins to go haywire. Scientists are now developing drug molecules to change that.

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