May 2023 Volume 19, Issue 5

May 2023 Front Cover

Volume 19, Issue 5 | May 2023

May 2023

In this Issue

Biologics

On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.

Chimera research opens new doors to understanding and treating disease

Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
A blue 3D rendering of the human digestive system shows the small intestine in orange and a zoomed-in image of the intestinal villi.

Taming the immune response to gluten to treat celiac disease

Researchers develop gluten-degrading enzymes to administer as drugs or incorporate into food and explore therapies that block downstream disease checkpoints.

Editor's Focus

A microscopic view of a family of four tardigrades of the species Hypsibius exemplaris swimming in a water droplet.

Tardigrades protect proteins on the brink of death

Tardigrades survive heat, freezing, and even space radiation. Now, researchers translate lessons learned from these creatures into more stable drug formulations and new health insights.

Disease Models

Daniel Promislow and Matt Kaeberlein stand in a field of purple flowers with three dogs.

Aging dogs provide insights for human longevity

Biogerontologist Matt Kaeberlein studies aging pets to determine how to improve healthspan in dogs and their humans.
Blue and green droplets of organoids against a black background.

Unraveling the molecular mechanisms of endometriosis

Bioengineer Linda Griffith creates tissue models to figure out what causes endometriosis and how to treat it.

Immunology

Circadian rhythm concept illustration with tiny characters. Day and night cycle scheme. Daily human body inner regulation schedule. Natural sleep and wake biological process. Abstract cartoon vector illustration.

Immunologists hack body rhythms for medicine

The success of vaccines and cancer treatments varies depending on the time of day they are delivered. Researchers now look to exploit circadian rhythms to improve health outcomes.
A syringe injects a vaccine from a vial bottle.

A new era of vaccine development

Pioneering approaches transform vaccine technologies and shape the future of disease prevention.

Editors Insight

A circle of many arms in business attire extended towards one another, hands stacked on top of each other.

In science, we go farther together

We should work to dispel the myth of the lone genius and embrace collaboration.
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Clear sample tubes are shown in a clear tote with red lids in a sample prep robot with a blue and silver industrial lab background.

The crucial role of sample preparation in biotherapy manufacturing

Discover how better sample preparation can unlock improved assay accuracy and analytical results.
A black mosquito is shown on pink human skin against a blurred green backdrop.

Discovering deeper insights into malaria research

Malaria continues to drive urgent research worldwide, with new therapies and tools emerging to combat the parasite’s complex lifecycle and global burden.
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