May 2023- Volume 19, Issue 5

In this Issue

Editor's Focus

A microscopic view of a family of four tardigrades of the species Hypsibius exemplaris swimming in a water droplet.

Tardigrades protect proteins on the brink of death

Tardigrades protect proteins on the brink of death

Tardigrades survive heat, freezing, and even space radiation. Now, researchers translate lessons learned from these creatures into more stable drug formulations and new health insights.

Disease Models

Daniel Promislow and Matt Kaeberlein stand in a field of purple flowers with three dogs.

Aging dogs provide insights for human longevity

Aging dogs provide insights for human longevity

Biogerontologist Matt Kaeberlein studies aging pets to determine how to improve healthspan in dogs and their humans.

Biologics

On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.

Chimera research opens new doors to understanding and treating disease

Chimera research opens new doors to understanding and treating disease

Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
A blue 3D rendering of the human digestive system shows the small intestine in orange and a zoomed-in image of the intestinal villi.

Taming the immune response to gluten to treat celiac disease

Taming the immune response to gluten to treat celiac disease

Researchers develop gluten-degrading enzymes to administer as drugs or incorporate into food and explore therapies that block downstream disease checkpoints.

Immunology

Circadian rhythm concept illustration with tiny characters. Day and night cycle scheme. Daily human body inner regulation schedule. Natural sleep and wake biological process. Abstract cartoon vector illustration.

Immunologists hack body rhythms for medicine

Immunologists hack body rhythms for medicine

The success of vaccines and cancer treatments varies depending on the time of day they are delivered. Researchers now look to exploit circadian rhythms to improve health outcomes.
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