May 2020 Volume 16, Issue 5
Volume 16, Issue 5 | May 2020
May 2020
In this Issue
Clinical Trials
Quashing brain cancer
Personalized cancer immunotherapy creates antigens from patient’s own cancer cellsASCENT rises above and beyond
Immunomedics to halt study due to ‘compelling efficacy’ of novel therapy for TNBCSocial distancing meets clinical trials
PPD subsidiary and Science 37 to provide virtual trial access to patients globallyThe FDA, trials and the coronavirus
COVID-19 causes agency to issue guidance for conducting clinical trialsContract Services
Meeting demand for neoantigens
GenScript launches neoantigen-specific peptide synthesis service for biotech and pharmaNew capabilities for Cambrex
Cambrex completes biopharmaceutical expansion at its Durham facilityViroclinics and DDL join forces
Two leading virology testing laboratories integrate to form new group serving global biopharmaceutical industryDiagnostics
A rapid testing option for COVID-19
VTT and MeVac work together to develop virus detectionAiming to outsmart cancer
Caris launches MI FOLFOXai, an AI-powered predictor of metastatic colorectal cancerBringing speed to coronavirus testing
BillionToOne says new COVID-19 protocol could unlock a million tests per dayCapsulomics teams up with Johns Hopkins University
$3.7M NIH-funded research will advance pre-cancer and cancer-detection technology licensed in 2019‘Hearing’ disease
Lab-on-a-chip monitors extracellular matrixDiscovery
Building compounds less expensively
Rice team publishes simple aziridination method for synthesizing pharmaceutical building blocksBiomarkers and bowel disease
Gilead and Second Genome partner to identify response biomarkers for IBD drug candidatesDynamic duo
Sosei Heptares chooses Discngine software to aid in GPCR-based chemogenomicsGWAS may create roadblock in MDD discovery
Popular minimal phenotyping method could inhibit identification of pathways specific to depressionResearch & Development
Plugging the leaks
UCSD team develops mini-gut organoids to answer questions about leaky gut and test a possible treatmentHeart smart
Papers address cardiac safety testing protocolsAn immunosuppressive interest
Newly published data support the potential of LNA-modified ASOs to block important immunosuppressive pathwayBridging the divide
New study identifies trigger that turns dormant cancer stem cells into active onesPreclinical
Clearing the checkpoints
Scholar Rock preclinical study shows SRK-181 can reverse immune cell exclusionIn search of further data
GBS Global Biopharma, NRC extend agreement for additional testing of cannabinoid formulations in Parkinson's diseasePositive pain relief
New compound may help reduce chronic opioid use and facilitate dose taperingStem cells to the rescue in hemophilia
Induced pluripotent stem cells show success in treating hemophilia A in miceFeature
Focus Feature on Gene Editing: Catching up on CRISPR
A roundup of recent CRISPR gene editing R&D news, plus a Q&A and two commentaries from experts in the fieldSpotlight on Stem Cells
A look at some recent stem cell-related R&D news and an update on the most notable stem cell research meeting of the yearEditor's Focus
Editor’s focus: The future of the face-to-face
The ongoing pandemic is doing ongoing harm not just to public health but to plans for healthcare and life-sciences conferences, but perhaps the changes can bring improvements and new ways of thinking about large professional meetingsCommentary
Out of order: What’s next?
We often have not learned harsh lessons from the past; will we this time as we endure and eventually come out the other side of the COVID-19 pandemic?Expert Insight: Moving toward 3D bioprinted cardiovascular tissue
Cardiac tissue engineering techniques, such as those that use 3D bioprinting, could be used to create functional constructs capable of re-establishing the structure and function of damaged myocardium following myocardial infarctionBusiness & Government Policy
An Asian collaboration
Regeneron and Zai Lab create regional strategic collaboration for REGN1979On the cutting edge
A roundup of instrumentation, software and other tools and technology newsStemming the threat of ARDS
Citius signs exclusive option with Novellus to license novel stem cell therapy for acute respiratory distress syndromeCCRM and panCELLa partner on new master cell banks
Collaborators aim to accelerate development of novel cell therapies and aid both academia and industry
