May 2012- Volume 8, Issue 5

May 2012

In this Issue

Feature

More about asm2012 and San Francisco

More about asm2012 and San Francisco

Additional information about the ASM 112th General Meeting and a few of the sites around San Francisco

Getting the big picture from small sources

Getting the big picture from small sources

American Society for Microbiology’s annual meeting covers a lot of ground

Diagnostics

Scratching out allergies

Scratching out allergies

Advaxis, Karolinska Institutet conduct research in allergic diseases

Roche throws in the towel

Roche throws in the towel

Company announces that tender offer for Illumina will not be extended

MMRF, TGen to lead multiple myeloma study

MMRF, TGen to lead multiple myeloma study

The Multiple Myeloma Research Foundation (MMRF) recently announced a multi-year oncology research partnership with several partners

GE ropes in Texas genomics company

GE ropes in Texas genomics company

GE Healthcare completes acquisition of SeqWright, expanding capabilities in fast- growing molecular diagnostic segment

BMS opts for MULTI-ARRAY

BMS opts for MULTI-ARRAY

Bristol-Myers Squibb and Meso Scale Discovery to develop diagnostic assays for Alzheimer’s disease

B cells on the A-list

B cells on the A-list

HTG Molecular Diagnostics and Sanofi US collaborate to identify B-cell malignancy biomarkers

Special Reports

Going for multiple shots on goal

Going for multiple shots on goal

Drugmakers seek more than one application for compounds in early phase of development

Research & Development

Spectrum diversifies its revenue

Spectrum diversifies its revenue

Spectrum Pharmaceuticals acquires Allos Therapeutics for $206 million

Clinical-stage collaboration

Clinical-stage collaboration

AstraZeneca’s MedImmune subsidiary partners with Amgen to commercialize early- and late-stage clinical inflammation portfolio

Shire stakes a claim

Shire stakes a claim

Company acquires hematology- focused FerroKin BioScience in deal worth as much as $325 million; also licenses CNS program from Heptares in potential $190 million agreement

AMRI licenses anticancer tubulin inhibitor program to Bessor Pharma

AMRI licenses anticancer tubulin inhibitor program to Bessor Pharma

Agreement demonstrates AMRI’s strategic plan to advance the clinical development of its compounds and programs

Sigma-Aldrich acquires Research Organics, strengthens portfolio of PharmaGrade raw materials

Sigma-Aldrich acquires Research Organics, strengthens portfolio of PharmaGrade raw materials

Sigma-Aldrich Corp. announced in April that it has acquired all outstanding shares of Cleveland, Ohio-based, Research Organics Inc., to expand the company’s buffer production capacity and to increase its portfolio of PharmaGrade raw materials for the biopharmaceutical and diagnostic markets

A deal with 20/20 vision

A deal with 20/20 vision

Bausch + Lomb acquires ISTA, gains strong ophthalmic portfolio

Omics & Systems Biology

Researchers have the stomach for cancer

Researchers have the stomach for cancer

Duke-NUS, NCCS-led team discovers stomach cancer gene mutations

A virtual encyclopedia

A virtual encyclopedia

The Cancer Cell Line Encyclopedia, a project launched by Novartis and the Broad Institute, lends knowledge to cancer drug development

Cars, remote controls and McDonalds

Cars, remote controls and McDonalds

Obesity and type 2 diabetes targeted by Ember Therapeutics’ license of brown fat technology and IP from the Joslin Diabetes Center

PROOF positive about working with Adiga

PROOF positive about working with Adiga

PROOF Centre and Adiga Life Sciences launch biomarker discovery collaboration related to allergies

Agilent and FAPESP fund life-science research projects in Brazil

Agilent and FAPESP fund life-science research projects in Brazil

Agilent Technologies Inc. and FAPESP, the São Paulo Research Foundation, recently announced the selection of two jointly funded research projects

Government Watch

President Obama signs JOBS Act

President Obama signs JOBS Act

Legislation holds good news for biopharma, biotech startups

Under the looking glass

Under the looking glass

Senate panel voices concerns for 2013 NIH budget

COMMENTARY: Laws of nature muddle patent certainty

COMMENTARY: Laws of nature muddle patent certainty

After a long wait, the U.S. Supreme Court issued its opinion in Mayo v. Prometheus, an important intellectual property case for the biotechnology industry

Mayo yes, Myriad maybe

Mayo yes, Myriad maybe

Supreme Court agrees with Mayo’s stance on Prometheus patent claims; sends Myriad Genetics case back to the Federal Circuit

Editor's Focus

Michigan university, lawmakers at impasse over hESCs

Michigan university, lawmakers at impasse over hESCs

In March, Michigan’s House Appropriations Subcommittee on Higher Education said it may withhold $7 million of performance funding from the 2012/2013 state budget for the University of Michigan (U-M) and Michigan State University if U-M does not disclose the number of hESCs the school is using in its research.

Commentary

Out of Order: Patently absurd

Out of Order: Patently absurd

Patents do not stifle innovation any more than copyright laws stifle creativity. In a similar vein, homeownership does not stifle homelessness, and marriage does not necessarily stifle infidelity.

Paradigm shift: Rethinking type 2 diabetes as a heterogeneous disease

Paradigm shift: Rethinking type 2 diabetes as a heterogeneous disease

The only way we will see true, long-term success in treating diabetes is by fundamentally rethinking this disease and shifting our focus to pursue a targeted, personalized approach to prevention, diagnosis and treatment.

Tools & Technology

Bruker in 3D

Bruker in 3D

Company announces acquisition of SkyScan, launches Micro-CT 3D X-ray imaging systems for life-science and materials research

Beckman Coulter sets sail with Blue Ocean

Beckman Coulter sets sail with Blue Ocean

Acquisition expands company’s flow cytometry portfolio

Sequencing in the palm of your hand?

Sequencing in the palm of your hand?

QuantuMDx Group and A*STAR Institute Of Microelectronics aim to bring nanowire-based DNA sequencing to market

BioClinica’s PET project

BioClinica’s PET project

Company inks collaborative deal to leverage Mirada’s advanced image analysis capabilities

Japan’s Transparent, Molecular Response to launch 3D cell culture system for cancer applications

Japan’s Transparent, Molecular Response to launch 3D cell culture system for cancer applications

Transparent Inc. and Molecular Response Laboratories (MRL) announced in late March that they launch Cell-able Oncology, a novel 3D cell culture system for pharmaceutical researchers and medical professionals.

Crystal-clear acquisitions

Crystal-clear acquisitions

Corning Life Sciences to further broaden offerings with acquisition of majority of BD Discovery Labware

Global News

Across the (other) pond

Across the (other) pond

Researchers from Canada and Japan reach across the Pacific Ocean to join forces in the development of stem-cell epigenetics

ADCs for PBD

ADCs for PBD

PolyTherics will collaborate with Spirogen to develop novel anti-cancer antibody-drug conjugates

A French-American alliance

A French-American alliance

Multicenter collaboration to target dendritic cells for therapeutic vaccines
Israeli researchers 

develop vaccine to fight cancer

Israeli researchers develop vaccine to fight cancer

Israeli researchers develop vaccine to fight cancer

Vaxil Biotherapeutics, U of Tel Aviv team up on vaccine targeting MUC1

Forming a pharma fund

Forming a pharma fund

Index Ventures, GSK and J&J align to make $240 million in venture-capital funding available to life-science companies with early-stage assets
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