May 2012 Volume 8, Issue 5

Volume 8, Issue 5 | May 2012

May 2012

In this Issue

Government Watch

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Mayo yes, Myriad maybe

Supreme Court agrees with Mayo’s stance on Prometheus patent claims; sends Myriad Genetics case back to the Federal Circuit
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President Obama signs JOBS Act

Legislation holds good news for biopharma, biotech startups
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Under the looking glass

Senate panel voices concerns for 2013 NIH budget
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COMMENTARY: Laws of nature muddle patent certainty

After a long wait, the U.S. Supreme Court issued its opinion in Mayo v. Prometheus, an important intellectual property case for the biotechnology industry

Tools & Technology

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Crystal-clear acquisitions

Corning Life Sciences to further broaden offerings with acquisition of majority of BD Discovery Labware
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Bruker in 3D

Company announces acquisition of SkyScan, launches Micro-CT 3D X-ray imaging systems for life-science and materials research
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Beckman Coulter sets sail with Blue Ocean

Acquisition expands company’s flow cytometry portfolio
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Sequencing in the palm of your hand?

QuantuMDx Group and A*STAR Institute Of Microelectronics aim to bring nanowire-based DNA sequencing to market
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BioClinica’s PET project

Company inks collaborative deal to leverage Mirada’s advanced image analysis capabilities
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Japan’s Transparent, Molecular Response to launch 3D cell culture system for cancer applications

Transparent Inc. and Molecular Response Laboratories (MRL) announced in late March that they launch Cell-able Oncology, a novel 3D cell culture system for pharmaceutical researchers and medical professionals.

Research & Development

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A deal with 20/20 vision

Bausch + Lomb acquires ISTA, gains strong ophthalmic portfolio
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Spectrum diversifies its revenue

Spectrum Pharmaceuticals acquires Allos Therapeutics for $206 million
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Clinical-stage collaboration

AstraZeneca’s MedImmune subsidiary partners with Amgen to commercialize early- and late-stage clinical inflammation portfolio
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Shire stakes a claim

Company acquires hematology- focused FerroKin BioScience in deal worth as much as $325 million; also licenses CNS program from Heptares in potential $190 million agreement
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AMRI licenses anticancer tubulin inhibitor program to Bessor Pharma

Agreement demonstrates AMRI’s strategic plan to advance the clinical development of its compounds and programs
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Sigma-Aldrich acquires Research Organics, strengthens portfolio of PharmaGrade raw materials

Sigma-Aldrich Corp. announced in April that it has acquired all outstanding shares of Cleveland, Ohio-based, Research Organics Inc., to expand the company’s buffer production capacity and to increase its portfolio of PharmaGrade raw materials for the biopharmaceutical and diagnostic markets

Global News

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Forming a pharma fund

Index Ventures, GSK and J&J align to make $240 million in venture-capital funding available to life-science companies with early-stage assets
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Across the (other) pond

Researchers from Canada and Japan reach across the Pacific Ocean to join forces in the development of stem-cell epigenetics
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ADCs for PBD

PolyTherics will collaborate with Spirogen to develop novel anti-cancer antibody-drug conjugates
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A French-American alliance

Multicenter collaboration to target dendritic cells for therapeutic vaccines

Israeli researchers develop vaccine to fight cancer

Vaxil Biotherapeutics, U of Tel Aviv team up on vaccine targeting MUC1

Editor's Focus

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Michigan university, lawmakers at impasse over hESCs

In March, Michigan’s House Appropriations Subcommittee on Higher Education said it may withhold $7 million of performance funding from the 2012/2013 state budget for the University of Michigan (U-M) and Michigan State University if U-M does not disclose the number of hESCs the school is using in its research.

Feature

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Getting the big picture from small sources

American Society for Microbiology’s annual meeting covers a lot of ground
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More about asm2012 and San Francisco

Additional information about the ASM 112th General Meeting and a few of the sites around San Francisco

Commentary

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Out of Order: Patently absurd

Patents do not stifle innovation any more than copyright laws stifle creativity. In a similar vein, homeownership does not stifle homelessness, and marriage does not necessarily stifle infidelity.
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Paradigm shift: Rethinking type 2 diabetes as a heterogeneous disease

The only way we will see true, long-term success in treating diabetes is by fundamentally rethinking this disease and shifting our focus to pursue a targeted, personalized approach to prevention, diagnosis and treatment.

Diagnostics

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GE ropes in Texas genomics company

GE Healthcare completes acquisition of SeqWright, expanding capabilities in fast- growing molecular diagnostic segment
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BMS opts for MULTI-ARRAY

Bristol-Myers Squibb and Meso Scale Discovery to develop diagnostic assays for Alzheimer’s disease
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B cells on the A-list

HTG Molecular Diagnostics and Sanofi US collaborate to identify B-cell malignancy biomarkers
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Scratching out allergies

Advaxis, Karolinska Institutet conduct research in allergic diseases
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Roche throws in the towel

Company announces that tender offer for Illumina will not be extended
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MMRF, TGen to lead multiple myeloma study

The Multiple Myeloma Research Foundation (MMRF) recently announced a multi-year oncology research partnership with several partners

Omics & Systems Biology

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Researchers have the stomach for cancer

Duke-NUS, NCCS-led team discovers stomach cancer gene mutations
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A virtual encyclopedia

The Cancer Cell Line Encyclopedia, a project launched by Novartis and the Broad Institute, lends knowledge to cancer drug development
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Cars, remote controls and McDonalds

Obesity and type 2 diabetes targeted by Ember Therapeutics’ license of brown fat technology and IP from the Joslin Diabetes Center
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PROOF positive about working with Adiga

PROOF Centre and Adiga Life Sciences launch biomarker discovery collaboration related to allergies
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Agilent and FAPESP fund life-science research projects in Brazil

Agilent Technologies Inc. and FAPESP, the São Paulo Research Foundation, recently announced the selection of two jointly funded research projects

Special Reports

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Going for multiple shots on goal

Drugmakers seek more than one application for compounds in early phase of development
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