March 2021 Volume 17, Issue 3

March 2021 cover

Volume 17, Issue 3 | March 2021

March 2021

In this Issue

Diagnostics

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A different kind of TROLL

APIS and Moffitt pair up to assess TROLL lncRNAs as predictive biomarkers in cancer
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Bringing down the cost of cancer?

NuView’s theranostics approach could make cancer diagnosis and treatment more affordable
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Global effort on a neglected tropical disease

Health partners team up to speed up development of new schistosomiasis test
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A first-in-class diagnostic for Parkinson’s disease

AC Immune Initiates Clinical Study of ACI-12589 PET imaging tracer

Preclinical

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Novel neuroprotection from Noveome

Data show full complement ST266 biologic offers better neuroprotection than fractionated formats
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Developing antibodies against SARS-CoV-2

DIOS-202 and DIOS-203 have been engineered for high potency and potential for avoiding escape mutants
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UC San Diego researchers target rare form of autism

Study could lead to future treatment for autism spectrum disorder that mostly affects girls

Tools & Technology

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The three dimensions: Impact, metrics, and process

Collaborative project model helps assess user experience maturity
Scientists in a laboratory using advanced antibody library screening technology with digital data analysis.

UCB acquires Specifica's antibody library platform

UCB secures an exclusive antibody library from Specifica to enhance its therapeutic antibody discovery pipeline.

Bringing biologics into the wearable device world

Clinical trial data demonstrate potential for BD Libertas wearable drug delivery system 

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Tools and services making the rounds

Find out about new offerings from BioTek, Repligen, Flow Eighteen38, and Cresset

Clinical Trials

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Antibody against Alzheimer’s

Lilly’s donanemab Phase 2 trial brings positive results
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Funding the jump to digital

Series C round to support Medable's plans for improving clinical trial technologies and options

Roflumilast foam advances to Phase 3

Data show that roflumilast foam provides significant improvement for seborrheic dermatitis

Discovery

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Blending datasets for better research

AI collaboration seeks to improve access to COVID-19 datasets across institutions

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Single-cell sequencing vs. Schistosoma mansoni

Cell atlas of tropical disease parasite could highlight new targets for treatment
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Autism answers within genetic disorders

Collaboration aims at drug discovery pipeline for monogenic causes of autism

Harnessing Electricity-Producing Bacteria

Potential exists for better detection and understanding of human disease

Special Reports

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Special Report on Clinical Trials: Delving into decentralization

Pandemic perils accelerate digital adoption in clinical trials

Feature

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Focus Feature on Cancer

We explore advances in women’s cancers in addition to other recent oncology news

Editor's Focus

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Cancer and clinical trials in the spotlight

March is still the month where we put extra attention on cancer, but the landscape is different in a pandemic
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Out of order: Beyond exhausted

While there will no doubt be and end, the COVID pandemic is tiring all of us out right now

Commentary

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Commentary: As COVID-19 research evolves, so too will animal models

Infectious disease researchers must expand the repertoire of animal models to advance their research
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How new alternative methods are changing drug safety testing.
 Can animal testing be replaced? Discover how scientists are developing more human-relevant ways to predict drug toxicity earlier.
White laboratory mouse standing in a petri dish in a laboratory, illustrating a rodent model commonly used in scientific and preclinical studies.
Learn about common challenges and proper maintenance practices for catheterized rodent models.
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Learn why data quality, governance, and collaboration are critical to realizing AI’s potential across the drug discovery pipeline.
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