March 2021 Volume 17, Issue 3

March 2021 cover

Volume 17, Issue 3 | March 2021

March 2021

In this Issue

Diagnostics

A different kind of TROLL

APIS and Moffitt pair up to assess TROLL lncRNAs as predictive biomarkers in cancer

Bringing down the cost of cancer?

NuView’s theranostics approach could make cancer diagnosis and treatment more affordable

Global effort on a neglected tropical disease

Health partners team up to speed up development of new schistosomiasis test

A first-in-class diagnostic for Parkinson’s disease

AC Immune Initiates Clinical Study of ACI-12589 PET imaging tracer

Preclinical

Novel neuroprotection from Noveome

Data show full complement ST266 biologic offers better neuroprotection than fractionated formats

Developing antibodies against SARS-CoV-2

DIOS-202 and DIOS-203 have been engineered for high potency and potential for avoiding escape mutants

UC San Diego researchers target rare form of autism

Study could lead to future treatment for autism spectrum disorder that mostly affects girls

Tools & Technology

The three dimensions: Impact, metrics, and process

Collaborative project model helps assess user experience maturity

Specifica sells antibody library platform to UCB

The Generation 3 Library Platform will boost UCB’s discovery efforts

Bringing biologics into the wearable device world

Clinical trial data demonstrate potential for BD Libertas wearable drug delivery system 

Tools and services making the rounds

Find out about new offerings from BioTek, Repligen, Flow Eighteen38, and Cresset

Clinical Trials

Antibody against Alzheimer’s

Lilly’s donanemab Phase 2 trial brings positive results

Funding the jump to digital

Series C round to support Medable's plans for improving clinical trial technologies and options

Roflumilast foam advances to Phase 3

Data show that roflumilast foam provides significant improvement for seborrheic dermatitis

Discovery

Blending datasets for better research

AI collaboration seeks to improve access to COVID-19 datasets across institutions

Single-cell sequencing vs. Schistosoma mansoni

Cell atlas of tropical disease parasite could highlight new targets for treatment

Autism answers within genetic disorders

Collaboration aims at drug discovery pipeline for monogenic causes of autism

Harnessing Electricity-Producing Bacteria

Potential exists for better detection and understanding of human disease

Special Reports

Special Report on Clinical Trials: Delving into decentralization

Pandemic perils accelerate digital adoption in clinical trials

Feature

Focus Feature on Cancer

We explore advances in women’s cancers in addition to other recent oncology news

Editor's Focus

Cancer and clinical trials in the spotlight

March is still the month where we put extra attention on cancer, but the landscape is different in a pandemic

Out of order: Beyond exhausted

While there will no doubt be and end, the COVID pandemic is tiring all of us out right now

Commentary

Commentary: As COVID-19 research evolves, so too will animal models

Infectious disease researchers must expand the repertoire of animal models to advance their research
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A 3D illustration of two DNA strands in a transparent bubble

Overcoming barriers in gene therapy 

Advanced gene editing, delivery, and analytical tools are driving better gene therapies.
An illustration of the human brain

A multiomic approach to profiling brain tumors

Probing the molecular drivers of brain metastasis reveals novel therapeutic targets.
A 3D illustration of purple-colored cancer cells surrounded by transparent immune cells with yellow nuclei

Enhancing immune cell profiling with digital technologies 

Software innovations help researchers decode immune complexity in cancer.
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