March 2020 Volume 16, Issue 3

Volume 16, Issue 3 | March 2020

March 2020

In this Issue

Feature

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AACR 2020 Show Preview: Crafting better cancer care

The AACR Annual Meeting covers the best in cutting edge cancer research and care
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Cancer therapies and insights up top

A roundup of recent research and development efforts in brain and lung cancers

Commentary

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Out of order: Developing solutions

As COVID-19 spreads, it can be a reminder that science and health research are community efforts, and to optimize our opportunities for success and serendipity, we must open that community as widely as we can
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MARKET INSIGHT: Key happenings in various markets and pipelines

A roundup of various insights from London-based data and analytics company GlobalData over the past couple months in multiple sectors of pharma, biotech and life sciences

Research & Development

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Take it from the top

Purdue University team creates tumor model of pancreatic cancer that elucidates disease progression from the beginning
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Potent pathogens

Researchers take aim at antibiotic-resistant bacteria
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Getting the skinny on glutamate

A new sensor technique enables the measurement of glutamate usage by brain cells for the first time
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One swab, many results

Mawi DNA taps CosmosID to evaluate its iSwab-Microbiome sample collection offering

Discovery

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Deactivating liver fibrosis

UC San Diego researchers find transcription factors that can halt accumulation of liver scarring and encourage healing
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Cell by cell

Researchers release a single-cell atlas examining changes in gene expression in Alzheimer’s disease beyond neurons
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AI and antibodies align

Three-year collaboration capitalizes on AI to develop therapeutic monoclonal antibodies
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Aiding drug discovery

Almirall and Iktos announce a research collaboration for new drug design
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Seeking candidates for Takeda

Integrated drug discovery collaboration will focus on Takeda’s four core therapeutic areas

Clinical Trials

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Fighting back against FOP

Regeneron reports encouraging garetosmab Phase 2 results in patients with ultra-rare bone disease
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New possibilities in women’s health

SCYNEXIS studies a new candidate in the fight against yeast infection
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Peanut problem

Company tests peanut allergy therapy for children
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A good start for fosciclopirox

CicloMed shares Phase 1 results of its lead candidate in bladder cancer
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Fighting COVID-19 effectively

Worldwide research and collaboration needed to combat the coronavirus, says GlobalData

Editor's Focus

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Editor’s Focus: Let’s talk about the C-word, shall we?

Cancer news and events are the name of the game in much of the March issue of DDNews

Special Reports

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Special Report on Proteomics: Profiles in prognostication

Protein biomarkers go in search of clinical validity

Contract Services

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Partners wanted for base editing platform

Horizon wants to assess state of the technology and guide its future shape
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An IP partnership

Arctoris partners with Molecule to tackle the innovation crisis in drug discovery and development
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Monoclonal movements

GHO Capital invests in FairJourney, provider of monoclonal antibody discovery services

Diagnostics

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A ‘liquid’ asset

Liquid biopsy aims to accelerate biomarker-driven precision cancer therapies
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Zeroing in on prostate cancer

Validation study recently completed on miR Scientific’s Sentinel tests
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Eyes are windows to the...brain?

C. Light Technologies uses retinal tracking and AI as a new tactic for neurological diagnosis

Preclinical

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All that glitters

Clene Nanomedicine’s CNM-Au8 gold nanocrystals effectively induce remyelination in preclinical models
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Cue up a potential answer to fighting tumors

Cue Biopharma’s preclinical and translational data support potential of CUE-101 in HPV16-related malignancies
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Saving the brain

Study shows more effective, safer way to develop stem cells for treating brain damage
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INDY inhibition attenuates diet-induced NASH

Eternygen presents data positioning mINDY inhibitors as novel therapeutic option in NASH

Business & Government Policy

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Diabetes deterrent

Gene therapy approach reprograms beta cells in the pancreas
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On the cutting edge

A roundup of instrumentation, software and other tools and technology news
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Promoting more cancer R&D

Start Codon joins Cancer Research UK’s Entrepreneurial Programmes Initiative
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Turning bad fat into good fat

Purdue alumnus makes an investment that could help curb obesity and diabetes
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Understanding drug impurities: types, sources, and analytical strategies

Unseen and often unexpected, drug impurities can slip in at every drug development stage, making their detection and control essential.
Laboratorian with a white coat and blue gloves pipettes green liquid into a beaker with multicolored liquids in beakers and tubes in the blue-tinged, sterile laboratory background.

Discovering cutting-edge nitrosamine analysis in pharmaceuticals

New tools help researchers detect and manage harmful nitrosamine impurities in drugs such as monoclonal antibodies.
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