March 2020- Volume 16, Issue 3
In this Issue
Research & Development
Potent pathogens
Potent pathogens
Researchers take aim at antibiotic-resistant bacteria
Getting the skinny on glutamate
Getting the skinny on glutamate
A new sensor technique enables the measurement of glutamate usage by brain cells for the first time
One swab, many results
One swab, many results
Mawi DNA taps CosmosID to evaluate its iSwab-Microbiome sample collection offering
Take it from the top
Take it from the top
Purdue University team creates tumor model of pancreatic cancer that elucidates disease progression from the beginning
Business & Government Policy
Diabetes deterrent
Diabetes deterrent
Gene therapy approach reprograms beta cells in the pancreas
On the cutting edge
On the cutting edge
A roundup of instrumentation, software and other tools and technology news
Promoting more cancer R&D
Promoting more cancer R&D
Start Codon joins Cancer Research UK’s Entrepreneurial Programmes Initiative
Turning bad fat into good fat
Turning bad fat into good fat
Purdue alumnus makes an investment that could help curb obesity and diabetes
Discovery
Cell by cell
Cell by cell
Researchers release a single-cell atlas examining changes in gene expression in Alzheimer’s disease beyond neurons
AI and antibodies align
AI and antibodies align
Three-year collaboration capitalizes on AI to develop therapeutic monoclonal antibodies
Aiding drug discovery
Aiding drug discovery
Almirall and Iktos announce a research collaboration for new drug design
Seeking candidates for Takeda
Seeking candidates for Takeda
Integrated drug discovery collaboration will focus on Takeda’s four core therapeutic areas
Deactivating liver fibrosis
Deactivating liver fibrosis
UC San Diego researchers find transcription factors that can halt accumulation of liver scarring and encourage healing
Clinical Trials
Fighting back against FOP
Fighting back against FOP
Regeneron reports encouraging garetosmab Phase 2 results in patients with ultra-rare bone disease
New possibilities in women’s health
New possibilities in women’s health
SCYNEXIS studies a new candidate in the fight against yeast infection
Peanut problem
Peanut problem
Company tests peanut allergy therapy for children
A good start for fosciclopirox
A good start for fosciclopirox
CicloMed shares Phase 1 results of its lead candidate in bladder cancer
Fighting COVID-19 effectively
Fighting COVID-19 effectively
Worldwide research and collaboration needed to combat the coronavirus, says GlobalData
Preclinical
Saving the brain
Saving the brain
Study shows more effective, safer way to develop stem cells for treating brain damage
INDY inhibition attenuates diet-induced NASH
INDY inhibition attenuates diet-induced NASH
Eternygen presents data positioning mINDY inhibitors as novel therapeutic option in NASH
All that glitters
All that glitters
Clene Nanomedicine’s CNM-Au8 gold nanocrystals effectively induce remyelination in preclinical models
Cue up a potential answer to fighting tumors
Cue up a potential answer to fighting tumors
Cue Biopharma’s preclinical and translational data support potential of CUE-101 in HPV16-related malignancies
Feature
Cancer therapies and insights up top
Cancer therapies and insights up top
A roundup of recent research and development efforts in brain and lung cancers
AACR 2020 Show Preview: Crafting better cancer care
AACR 2020 Show Preview: Crafting better cancer care
The AACR Annual Meeting covers the best in cutting edge cancer research and care
Editor's Focus
Editor’s Focus: Let’s talk about the C-word, shall we?
Editor’s Focus: Let’s talk about the C-word, shall we?
Cancer news and events are the name of the game in much of the March issue of DDNews
Special Reports
Special Report on Proteomics: Profiles in prognostication
Special Report on Proteomics: Profiles in prognostication
Protein biomarkers go in search of clinical validity
Contract Services
Partners wanted for base editing platform
Partners wanted for base editing platform
Horizon wants to assess state of the technology and guide its future shape
An IP partnership
An IP partnership
Arctoris partners with Molecule to tackle the innovation crisis in drug discovery and development
Monoclonal movements
Monoclonal movements
GHO Capital invests in FairJourney, provider of monoclonal antibody discovery services
Diagnostics
A ‘liquid’ asset
A ‘liquid’ asset
Liquid biopsy aims to accelerate biomarker-driven precision cancer therapies
Zeroing in on prostate cancer
Zeroing in on prostate cancer
Validation study recently completed on miR Scientific’s Sentinel tests
Eyes are windows to the...brain?
Eyes are windows to the...brain?
C. Light Technologies uses retinal tracking and AI as a new tactic for neurological diagnosis
Commentary
Out of order: Developing solutions
Out of order: Developing solutions
As COVID-19 spreads, it can be a reminder that science and health research are community efforts, and to optimize our opportunities for success and serendipity, we must open that community as widely as we can
MARKET INSIGHT: Key happenings in various markets and pipelines
MARKET INSIGHT: Key happenings in various markets and pipelines
A roundup of various insights from London-based data and analytics company GlobalData over the past couple months in multiple sectors of pharma, biotech and life sciences
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