March 2018 Volume 14, Issue 3
Volume 14, Issue 3 | March 2018
March 2018
In this Issue
Discovery
An ‘intelligent’ approach
AI and machine-learning approaches seem to be an industry theme for Q1 2018Working the crowd
Open-access communities launch to support drug discovery effortsCompugen catches a new checkpoint
Discovery of ILDR2 as a novel immune checkpoint and potential for autoimmune diseases published in back-to-back papersGetting the ‘Akt’ straight in angiogenesis
Sanford Burnham team details how the R-Ras/Akt pathway triggers and supports new blood vessel growthPushing paper
A roundup of discovery-related research published recently in journalsResearch & Development
‘Virus-cracking’ molecules
Indiana University team fights hepatitis BProtein power
New methods emerge to manufacture therapeutic proteinsHave a (mouse) heart!
Single-cell characterization of non-myocyte heart cells offers new insights into structure and functionAre immortalized stem cells poor surrogates?
Deleted gene that immortalizes MSCs may be critical to their functionCorning introduces new dissolvable microcarriers
Product offering is designed for improved large-scale cell expansionPieris and Seattle Genetics announce immuno-oncology collaboration
Companies to evaluate novel bispecific agents combining anticalin technology with select antibodiesPreclinical
Tag team against Usher syndrome
Foundation Fighting Blindness and ProQR enter into a partnership to develop QR-421a for genetic disease‘Not just science, but an art form’
Kinase inhibitor may prove useful in treating rare genetic diseaseIn with the new
RWTH explores biohybrid development and digital notebook optionDouble the good news
BioLineRx’s BL-8040 and AGI-134 programs boost survival in preclinical studiesChina- and U.S.-bound for RX-0201
Rexahn announces collaboration with Zhejiang Haichang Biotechnology for development of Archexin to treat hepatocellular carcinomaA deal for artificial lymph node technology
ProBioGen and TEVA enter into research license deal on tech to assess drug effects on the immune systemFeature
Spotlight on Oncology
New discoveries in cancer-related targets and pathways, plus other recent news in oncology R&D and clinical trialsSpecial Focus on Neuroscience and Neurology
Looking at recent cutting-edge research in potential therapeutics for neurological conditions, plus additional news on autism breakthroughs, addiction treatment and moreEditor's Focus
Editor’s focus: So much to share
A tour of what we have to offer you in our largest-ever issue of the magazine, from neurology to oncology and plenty of other places in the pharma and biotech worldContract Services
Coming together in contract services
A roundup of mergers and alliance deals in the contract services and pharma consulting spacesInnovate UK confident in Cobra
Cobra Biologics receives two separate grants from British innovation funderPresenting a plan for growth
Vetter introduces South Korea’s pharma and biotech community to company managementKicking up clinical capture
IACT Health selects Alpha Clinical Systems ACS360 e-source platform for trial data captureBusiness & Government Policy
NHGRI: Seeing 2020
Strategic plan aims to engage experts and diverse communities to identify paradigm-shifting areas of genomicsSupporting science startups
Elsevier welcomes six biotech and pharma companies to The HiveOn the cutting edge
A roundup of instrumentation, software and other tools and technology newsPatent Docs: The CRISPR chronicles
The Broad Institute wins one and loses oneFDA approves record number of personalized medicines in 2017
Personalized medicines now account for more than one in four new drug approvalsClinical Trials
Viral suppression
Study investigates two new drugs for HIVReplacing a needle with a pill
Allergan achieves positive top-line Phase 3 results for oral CGRP receptor antagonist targeting acute treatment of migraineA digital path for studies
TriNetX tech helps Sanofi streamline clinical trial protocols, improve efficiency and extend digital strategyOut of the starting gate
A roundup of clinical trial startups and initial breakthroughsDiagnostics
A new ‘path’ for Parsortix
ANGLE and Abbott seek blood test for metastatic breast cancerA novel companion biomarker for glaucoma
Q BioMed signs exclusive option with Washington University related to growth differentiation factor-15Money for MeMed
$4M grant awarded to support transfer to manufacturing of MeMed’s pioneering point-of-care platformmicroRNAs for earlier diagnosis?
Dana-Farber/Brigham and Women’s team identifies set of seven microRNAs that could detect early-stage ovarian cancerFDA approval for Hologic’s Aptima
Assay for quantitation of hepatitis B viral load receives pre-market approvalCommentary
