March 2013 Volume 9, Issue 3

Volume 9, Issue 3 | March 2013

March 2013

In this Issue

Global News

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A breakup worth billons

Biogen Idec purchases Elan’s share in Tysabri franchise for more than $3 billion; Elan is already entertaining acquisition offers
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Addressing a growing need

Galapagos acquires Cangenix for $1.5 million
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European Lead Factory launched

Public-private partnership aims to accelerate early drug discovery
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Resistance really is futile

European partnership aims to re-enable antibiotics against resistant bacteria
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Uber-antibiotic duo

Sweden’s Pergamum collaborates with India’s Cadila Pharmaceuticals to develop novel peptides to treat infections

Research & Development

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Safer drugs, better cancer care

NanoSmart Pharmaceuticals and UCLA enter collaboration agreement for pediatric cancer drug development
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MAP leads to pot of gold

Allergan subsidiary, MAP Pharmaceuticals merger could be worth nearly $1 billion
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Marriage for MS treatment

Merck Serono and Opexa Therapeutics enter into $225 million drug development agreement
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Canada continues stem cell tradition

Toronto’s Stem Cell Therapeutics, Trillium propose merge to develop new drugs to combat AML, other cancers
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Maxing out with GVAX

Aduro acquires cancer vaccine assets from BioSante for $1 million

Omics & Systems Biology

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Meddling with medulloblastoma

Trio unites to seek metastasis biomarkers for common childhood brain tumors
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Heart-smart commercialization

Collaboration targets R&D of RNAi compound to treat cholesterol issues
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It’s only logical

King’s College London, Emerald Logic seek to develop predictive, discriminative Alzheimer’s model
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Drawing a better map

New technique pinpoints protein locations, helping scientists figure out their functions in live cells
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Glycomics on the map

Kyowa Hakko Kirin to fund projects exploiting Ezose’s GlycanMap technology

Commentary

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A genome’s got to know its limitations

Although we are believers in genomics, we suspect that it will take the conventional 20 years or so between investment in research and commercial exploitation. We also feel that application of genomics to healthcare delivery will take place by a large number of small steps, and not as a big bang. In short, a genome’s got to know its limitations.
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Out of Order: Didn’t see that coming

Too often, the industry’s hands appear to be tied when it comes to providing target markets with information, as regulatory agencies and advertising counsels argue that consumers aren’t capable of digesting this information. I think we’re not giving today’s consumers enough credit.

Editor's Focus

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Cancer patients: The heart of the matter

If you’re in a position to create treatments for cancer, what’s the silver bullet for you? Is it creating a safe and effective blockbuster drug that brings in the revenue your company needs to continue work on future drugs? Is it an altruistic quest for a cure?

Special Reports

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‘Good enough’ is no longer good enough

Trends in Cancer Research feature report Part 1 of 2: Aiming beyond the standard of care in oncology

Government Watch

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The USPTO uncertainty principle

Effects of changes in U.S. patent regime may take years to be fully understood, adjudicated
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FDA on a hot streak

U.S. regulators approved a record number of new drugs in 2012
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Taking it to the states

Pharmas and biotechs lobby state legislatures to limit generics, biosimilars

Diagnostics

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A deeper companionship

QIAGEN and Lilly enter into expanded collaboration relationship to develop and commercialize companion diagnostics
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When East meets West

Vela, Jefferson to combine experience for the development of molecular diagnostic assays
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Assay for AD

Amorfix and QPS to collaborate on Alzheimer’s disease project
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JPT Peptide, Institute for Medical Immunology partner on chronic fatigue syndrome

JPT Peptide Technologies GmbH, a wholly owned subsidiary of BioNTech AG, and the Institute for Medical Immunology at the Charité in Berlin recently announced a collaborative agreement to develop serological peptide markers for the differential diagnosis of chronic fatigue syndrome (CFS)

Feature

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A capitol idea -- AACR 2013 conference preview

AACR’s annual meeting in Washington, D.C., offers chance for education, networking and a public call for policy changes
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A capitol idea -- AACR 2013 conference preview (Part 2)

More information about the annual meeting and more photos from Washington, D.C.

Tools & Technology

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End-to-end workflow

Life Technologies acquires BAC, expands bioprocessing protein purification workflow
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Dealing with the data

Curie- Cancer, GenoSplice to target cancer genomics data via bioinformatics
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A P4 partnership

The Institute for Systems Biology and AB SCIEX partner to make medical care more ‘predictive, preventive, personalized and participatory’
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Adding new dimensions

Organovo and OHSU Knight Cancer Institute collaborate on biological models for cancer drug discovery and development
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