June 2020 Volume 16, Issue 6
Volume 16, Issue 6 | June 2020
June 2020
In this Issue
Clinical Trials
Well-tolerated tumor drug
Antibody therapeutic from Compugen demonstrates no dose-limiting toxicitiesOptimal OPTICs
ADVM-022 demonstrates efficacy, durability in OPTIC trial in wet AMDMore skin in the game
Libtayo shows promise for a second indicationUsher update
ProQR offers upbeat interim analysis in Phase 1/2 trial of QR-421a for Usher SyndromeInvestigating an IL-6 antibody
An update on Sanofi and Regeneron’s Kevzara trial in hospitalized COVID-19 patientsDiagnostics
A better test for COVID-19
Digital PCR solution cuts down on false negatives, may help in clinical trialsAgainst antibiotic resistance
Selux Diagnostics receives additional 9.6 million for rapid AST platformPutting the ‘AI’ in diagnostics
A look at the growing trend of integrating artificial intelligence and machine learning with diagnosticsBusiness & Government Policy
Broadening its footprint in biotech
Germany’s Sartorius acquires selected assets of Danaher Life SciencesOn the cutting edge
A roundup of instrumentation, software and other tools and technology newsQ&A: The challenges of a vaccine for COVID-19
DDN takes some time to speak with Amélie Boulais, vaccine platform marketing manager at Sartorius Stedim BiotechResearch & Development
Meaningful biomarkers
Precision medicine analyses show potential for Alzheimer’s drugAUM launches Knockdown Coronavirus
RNA could be the kryptonite to defeat COVID-19Building a biobank
Biogen, Broad Institute and Partners HealthCare create consortium for COVID-19 effortsTiming is everything
Suppression of immune system may be key to reducing COVID-19 severityDiscovery
Complementary cancer collaboration
Exscientia and SRI combine strengths for oncology drug discoveryRelying on RNAi
Vir and Alnylam identify RNAi development candidate targeting SARS-CoV-2Arrakis partners with Roche
Collaboration will use RNA-targeted small-molecule discovery platform for multiple targetsFurther success in malaria initiative
Optibrium and Intellegens report in-vitro validation of in-silico-generated compoundKnow your enemy
Team uses knowledge of how SARS-CoV-2 infects cells to identify drugs that could combat itManaging macrolactones
New database could aid large-molecule drug discovery and researchContract Services
A strong complement in China
Reaction Biology, PharmaCore Labs strike up collaboration agreementMaking a deal on ADCs
Trio Pharmaceuticals and Ajinomoto enter into development collaborationPreclinical
Data recommend RECCE 327
Synthetic antibiotic shows efficacy against priority antibiotic-resistant pathogenAn autoimmune option
Immutep and Batavia Biosciences reach LAG-3 immunotherapy milestoneNegative Data Prize is a positive?
Global Preclinical Data Forum says sharing negative science results is key to neuroscience progressFeature
Focus Feature on Cancer Research News
Recent happenings on the R&D front to better understand cancer and create oncology therapeuticsCommentary
Testing, testing, testing...1,2,3,4
Diagnostic testing is hotter news right now with COVID than perhaps ever before, but what does it all mean?Guest Commentary: Accelerating the pace of pharma innovation at a molecular level
Innovation isn’t just measured in the number of approvals, and looking at NMEs might be a better gauge of the ways in which drug discovery is currently thrivingSpecial Reports
Special Report on Cancer: Anticipating antibodies
Digging deeper into repertoires means tapping into Plan B (cell)Editor's Focus
Editor’s Focus: Cancer, COVID and change
Change is the name of the game in our understanding of cancer, the effect of COVID and the future of DDN magazine
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Unlocking laboratory efficiency: a complete guide to LIMS selection
Discover how to choose, implement, and optimize laboratory information management systems (LIMS) to streamline lab operations and ensure compliance.
Reliable fluid biomarkers strategies for clinical neuroscience research
Explore how validated fluid biomarker assays advance clinical research for neurological diseases.
Understanding drug impurities: types, sources, and analytical strategies
Unseen and often unexpected, drug impurities can slip in at every drug development stage, making their detection and control essential.
