June 2018 Volume 14, Issue 6
Volume 14, Issue 6 | June 2018
June 2018
In this Issue
Discovery
The next dimension in drug testing
Scripps scientists use 3D spheroids to better test cancer drugs’ efficacyXtalPi and Pfizer collaborate on AI
Aim is to develop artificial intelligence-powered molecular modeling tech for drug discoveryAn AI approach to malaria
Gates Foundation grant to fund work by Recursion and UC San Diego in malaria treatment discoveryIt’s molecular!
Fujitsu develops molecular simulation technology to effectively create new drug candidatesPreclinical
Episodic memory replay
Rats’ replay of events has implications for AD treatmentsInjectable nanos vs. tumors
Nanobiotix and Weill Cornell Medicine enter research collaboration‘Building a better ADC’
Sutro Biopharma advances STRO-001 and STRO-002 into the clinic against multiple cancer typesRelief for devastating skin disease?
Human placental-derived stem cells boost survival, collagen deposition in mouse models of RDEBNew data on ALG.APV-527 for solid tumors
Aptevo and Alligator present preclinical data for novel immunotherapy bispecific candidateBusiness & Government Policy
An agreement at last
Shire commits to Takeda’s latest acquisition offer of roughly $62 billionBeam launches into base editing
New company plans to build on CRISPR tech to enable single-letter editing of DNA and RNACelsius launches with $65M in financing
Company seeks to develop precision therapeutics for people with autoimmune diseases and cancerOn the cutting edge
A roundup of instrumentation, software and other tools and technology newsFate and MSK expand oncology license deal
Updated agreement to include gene-edited T cell immunotherapiesSpecial Reports
Special Report on Cancer: Aiming for avatars
Oncologists seek clarity via patient-derived modelsEditor's Focus
Editor’s focus: Medicines going digital?
Before we start getting too comfortable using terms like "digital therapeutics" or "digiceuticals" maybe we should establish exactly what they areCommentary
Guest commentary: Improving clinical trial design in acute pain
Biopharma companies must consider a great deal when designing a trial that will enable a pain medication to show significant treatment effect compared to placeboRats and me
There remains a place for animal testing with regard to human therapeutics, even as the space grows to use non-animal alternatives moreFeature
Spotlight on Oncology: Pushing the tumor boundaries
A roundup of very recent novel research in the field of oncologyClinical Trials
Phase 1 phenomenon
First-in-class EZH2 inhibitor demonstrates safety and efficacyIn pursuit of HIV
Inovio Pennvax-GP HIV vaccine sustained durable memory responses measured one year after the start of the clinical trialPotential game-changer for OA
Flexion Therapeutics explores current and future opportunities for Zilretta, a non-opioid injection for painFuture looking bright for eClinical solutions
Market to cross $4-billion mark by 2020, driven by unified cloud-based platforms with scalability and modularityResearch & Development
Triboluminescence at Purdue
Researchers create triboluminescence instrument to rapidly test whether drugs contain trace crystallinityRosalind Franklin has another growth spurt
University announces three new disease-based scientific additions to its research parkIllumina ‘tames’ a DRAGEN
Company gains Edico’s DRAGEN Bio-IT tech for next-generation sequencing in acquisitionDopamine receptors as cancer biomarker
HKBU develops iridium probes that could lead to novel early-detection technology for cancerDiagnostics
Expanding the value for Oncomine Dx
A pair of new deals with Daiichi and Takeda help move Thermo’s technology forwardExosomes to the rescue?
Minimally invasive test provides early breast cancer detectionG6PD deficiency diagnosis
PATH, Mologic work to identify malaria patients at risk of side effects from standard malaria treatmentAmarantus lines up future efforts for LymPro
The company is pursuing a license agreement with Leipzig University, as well as a second clinical studyContract Services
Recipharm teams up with Hadasit
Partnership created with the goal of delivering seamless chemical and clinical servicesRounding the oncology bases
CrownBio launches new humanized model, enters strategic partnership with Phanes and presents many posters at AACR 2018NanoString partners with CROs on DSP service
Expanded technology access program is a response to interest from leading biopharma companies and lab service providers
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