June 2017- Volume 13, Issue 6

In this Issue

Commentary

Bubbles that need some popping

Bubbles that need some popping

Scientific papers and presentations are good, but have we reached the point there are so many journals and so many conferences that we are losing serious ground with regard to how many of them are reputable, valuable and/or to be trusted?

Diagnostics

Using IL-1 genotypes to predict cardiovascular events

Using IL-1 genotypes to predict cardiovascular events

Findings of study by Interleukin Genetics enhance the understanding of the role of genetics in cardiovascular disease

A new option in NIPT

A new option in NIPT

Hamilton Robotics and Illumina collaborate on automated, next-gen workflow for prenatal testing

‘Scent of a cancer’

‘Scent of a cancer’

Hitachi and Hirotsu Bio Science round up roundworms to sniff out cancer

A weapon against antibiotic resistance

A weapon against antibiotic resistance

U.S. Department of Defense funds effort to create tool for differentiating bacterial infections from viral ones

Feature

Post-show wrap-up: Digging deep into IO at AACR

Post-show wrap-up: Digging deep into IO at AACR

Earlier-stage cancer programs remain a mainstay of American Association for Cancer Research (AACR) annual meeting generally, but immuno-oncology approaches stand out

Discovery

New answers on muscle regeneration

New answers on muscle regeneration

Research explaining why aged muscle loses ability to regenerate comes with caution

New progress with PAR2

New progress with PAR2

Collaborative work from Heptares and AstraZeneca reveals X-ray crystal structures of a GPCR of interest

Abeome and CDC collaborate on Zika antibody

Abeome and CDC collaborate on Zika antibody

The deal will leverage Abeome's AbeoMouse platform to generate novel monoclonal antibodies

Moving along with methyltransferase inhibitors

Moving along with methyltransferase inhibitors

Epizyme earns $10- million milestone payment from GSK under inhibitor deal

Clinical Trials

Head and neck ahead

Head and neck ahead

Trial combines Regeneron’s PD-1 inhibitor and Inovio’s T cell and immune activators in glioblastoma multiforme

Centralization in clinical trials

Centralization in clinical trials

ASCO and NCI partner to explore the potential of centralized coverage analysis

Bioequivalent patch for Alzheimer’s

Bioequivalent patch for Alzheimer’s

Corium reports positive preliminary results for alternate formulation of donepezil

Brings a tear to your eye

Brings a tear to your eye

Shire and Parion Sciences sign off on license agreement to advance P-321 for dry eye disease

Down with the resistance

Down with the resistance

SCY-078 proves effective against multidrug-resistant fungus

Preclinical

Triple scoop of early-stage data

Triple scoop of early-stage data

Immunovaccine, Idera and Sunesis all share preclinical research results at AACR 2017

In pursuit of pertussis prevention

In pursuit of pertussis prevention

Preclinical study shows SYN-005 offers protection from whooping cough

Galapagos presents GLPG1972 data at OARSI meeting

Galapagos presents GLPG1972 data at OARSI meeting

Compound is a potent, selective, orally available ADAMTS-5 inhibitor for osteoarthritis

Platelet partnership

Platelet partnership

Plasticell taps Kings College London for preclinical studies of its blood platelet substitute

Editor's Focus

History in the making

History in the making

FDA’s approval of Merck & Co.’s pembrolizumab marks a watershed moment, heralding the possible era of 'tumor-agnostic' drug approvals

Research & Development

A new agreement for old partners

A new agreement for old partners

InSphero and Pfizer to jointly develop predictive liver toxicology measurement tool

TSRI tests new drug-making methods

TSRI tests new drug-making methods

Chemists devise simple method for making sought-after boronic acid-based drugs and other products

Early immunotherapy

Early immunotherapy

Barcoding maps immune system components before cancer progresses

Gyros Protein and Luxembourg Bio sign distribution agreement

Gyros Protein and Luxembourg Bio sign distribution agreement

Deal for peptide synthesis reagents includes exclusive distribution of PurePep coupling agents in North America

Contract Services

Two for the top three

Two for the top three

INC and inVentiv sign merger agreement; combined company would be one of the top three CROs

Immuno-oncology growing on Horizon

Immuno-oncology growing on Horizon

Current and ongoing sales and service projects in IO realm represent nearly 40-percent increase

CRO on the move

CRO on the move

PPD combines units, creates apprenticeship, adds personnel

Business & Government Policy

A couple more indications for CB-839

A couple more indications for CB-839

Bristol-Myers Squibb and Calithera expand cancer deal into NSCLC and melanoma

Ireland makes strong push to host EMA

Ireland makes strong push to host EMA

Nation cites case for continuity as European Medicines Agency prepares to leave United Kingdom

On the cutting edge

On the cutting edge

A roundup of instrumentation, software and other tools and technology news

Boehringer Ingelheim strengthens early science portfolio

Boehringer Ingelheim strengthens early science portfolio

Long-term collaboration partnership with Peking University to harness new scientific discoveries in areas of high unmet medical need
Subscribe to Newsletter
Subscribe to our eNewsletters

Stay connected with all of the latest from Drug Discovery News.

November 2021 Issue Front Cover

Latest Issue  

• Volume 17 • Issue 11 • November 2021

November 2021

November 2021 Issue