June 2017 Volume 13, Issue 6
Volume 13, Issue 6 | June 2017
June 2017
In this Issue
Preclinical
In pursuit of pertussis prevention
Preclinical study shows SYN-005 offers protection from whooping coughGalapagos presents GLPG1972 data at OARSI meeting
Compound is a potent, selective, orally available ADAMTS-5 inhibitor for osteoarthritisPlatelet partnership
Plasticell taps Kings College London for preclinical studies of its blood platelet substituteTriple scoop of early-stage data
Immunovaccine, Idera and Sunesis all share preclinical research results at AACR 2017Business & Government Policy
A couple more indications for CB-839
Bristol-Myers Squibb and Calithera expand cancer deal into NSCLC and melanomaIreland makes strong push to host EMA
Nation cites case for continuity as European Medicines Agency prepares to leave United KingdomOn the cutting edge
A roundup of instrumentation, software and other tools and technology newsBoehringer Ingelheim strengthens early science portfolio
Long-term collaboration partnership with Peking University to harness new scientific discoveries in areas of high unmet medical needClinical Trials
Brings a tear to your eye
Shire and Parion Sciences sign off on license agreement to advance P-321 for dry eye diseaseDown with the resistance
SCY-078 proves effective against multidrug-resistant fungusCentralization in clinical trials
ASCO and NCI partner to explore the potential of centralized coverage analysisBioequivalent patch for Alzheimer’s
Corium reports positive preliminary results for alternate formulation of donepezilHead and neck ahead
Trial combines Regeneron’s PD-1 inhibitor and Inovio’s T cell and immune activators in glioblastoma multiformeSpecial Reports
Special Report on Cancer Metabolomics: Into the metabolic maelstrom
Metabolomics shifts from map-making to therapeutic strategizingFeature
Post-show wrap-up: Digging deep into IO at AACR
Earlier-stage cancer programs remain a mainstay of American Association for Cancer Research (AACR) annual meeting generally, but immuno-oncology approaches stand outDiscovery
New progress with PAR2
Collaborative work from Heptares and AstraZeneca reveals X-ray crystal structures of a GPCR of interestNew answers on muscle regeneration
Research explaining why aged muscle loses ability to regenerate comes with cautionAbeome and CDC collaborate on Zika antibody
The deal will leverage Abeome's AbeoMouse platform to generate novel monoclonal antibodiesMoving along with methyltransferase inhibitors
Epizyme earns $10- million milestone payment from GSK under inhibitor dealEditor's Focus
History in the making
FDA’s approval of Merck & Co.’s pembrolizumab marks a watershed moment, heralding the possible era of 'tumor-agnostic' drug approvalsResearch & Development
A new agreement for old partners
InSphero and Pfizer to jointly develop predictive liver toxicology measurement toolTSRI tests new drug-making methods
Chemists devise simple method for making sought-after boronic acid-based drugs and other productsEarly immunotherapy
Barcoding maps immune system components before cancer progressesGyros Protein and Luxembourg Bio sign distribution agreement
Deal for peptide synthesis reagents includes exclusive distribution of PurePep coupling agents in North AmericaContract Services
Two for the top three
INC and inVentiv sign merger agreement; combined company would be one of the top three CROsImmuno-oncology growing on Horizon
Current and ongoing sales and service projects in IO realm represent nearly 40-percent increaseCRO on the move
PPD combines units, creates apprenticeship, adds personnelDiagnostics
A weapon against antibiotic resistance
U.S. Department of Defense funds effort to create tool for differentiating bacterial infections from viral onesUsing IL-1 genotypes to predict cardiovascular events
Findings of study by Interleukin Genetics enhance the understanding of the role of genetics in cardiovascular diseaseA new option in NIPT
Hamilton Robotics and Illumina collaborate on automated, next-gen workflow for prenatal testing‘Scent of a cancer’
Hitachi and Hirotsu Bio Science round up roundworms to sniff out cancerCommentary
Bubbles that need some popping
Scientific papers and presentations are good, but have we reached the point there are so many journals and so many conferences that we are losing serious ground with regard to how many of them are reputable, valuable and/or to be trusted?
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Shining light on the subcellular proteome
Discover how innovative proteomics tools help researchers peer into once inaccessible organelles, allowing for new targets for drug discovery and development.
