June 2013- Volume 9, Issue 6

June 2013

In this Issue

Tools & Technology

Quidel acquires BioHelix Corp.

Quidel acquires BioHelix Corp.

Completion of the acquisition gains Quidel isothermal amplification platforms

Quicker than an NGS minute

Quicker than an NGS minute

QIAGEN acquires Ingenuity Systems, adding time-saving solution for analysis and interpretation of complex biological data

In it to win it

In it to win it

Research indicates that open competition can be used to drive innovation

Sanofi sets sights on translational medicine

Sanofi sets sights on translational medicine

Partnership with NextBio will incorporate patient ‘omics and clinical data into pharma’s Translational Medicine for Patients program

Feature

Commentary

Publishers announce changes, broader focus for DDNEWS

Publishers announce changes, broader focus for DDNEWS

There is something new about ddn...Our front cover this month shows a change, but it is more about ddn continuing to evolve with the news of the changing technology in pharma, biotech and life-science research

Hire education: Which came first, the university or the economy?

Hire education: Which came first, the university or the economy?

A knowledge-based economy cannot thrive with frictions imposed by millennium-old constraints. At the limits where no one has a degree or everyone has a degree, the consequences are clearly dire. Too much of a good thing is a bad thing, and perhaps that’s where we are today in the United States.

Your personal genome sequenced: Where do you go from here?

Your personal genome sequenced: Where do you go from here?

Rapid, informative and inexpensive DNA variation annotation represents the future for much of medical research, and will continue to serve as the basis for significant technology development in academic and industry settings.

Special Reports

DNA: A winding string of achievements

DNA: A winding string of achievements

Examining 60 years of scientific progress since the discovery of DNA

DNA: A winding string of achievements (continued)

DNA: A winding string of achievements (continued)

Additional stories examining 60 years of scientific progress since the discovery of DNA...and looking forward

Clinical Trials

Vetting the best candidates

Vetting the best candidates

Cancer Research UK and Clovis Oncology begin trial for breast and ovarian cancer drug

Take it from the PROs

Take it from the PROs

Study determines degree of patient involvement in implementing clinical trials for diabetes

A heart-felt boost

A heart-felt boost

Trevena and Forest Labs announce development collaboration for TRV027

Stemming the pain of osteoarthritis

Stemming the pain of osteoarthritis

RNL BIO’s stem cell product holds promise of a single-injection treatment for osteoarthritis

The new math in clinical studies

The new math in clinical studies

Mathematical modeling of time-to-tumor growth helps predict survival benefit of bevacizumab for patients with metastatic colorectal cancer

Research & Development

Fast-fail for success

Fast-fail for success

UCLA gets $9 million in NIMH funding to conduct fast-fail trials in autism spectrum disorders

Strength in numbers

Strength in numbers

According to analysts, pharmas and biotechs are turning to M&As and collaboration deals to fix ‘bloated, untenable’ R&D paradigm

Signing a sweet deal

Signing a sweet deal

Pharma giants Merck and Pfizer enter worldwide collaboration agreement to develop and commercialize investigational medicine for type 2 diabetes

Working in Concert

Working in Concert

Concert, Celgene to develop compounds for cancer, inflammation

New partner, new patent

New partner, new patent

Soligenix to expand biodefense and infectious disease product pipeline through collaboration with Intrexon

Global News

A novel Conceptus

A novel Conceptus

Bayer HealthCare signs $1.1-billion merger agreement with Conceptus Inc.

OPKO opts for PROLOR

OPKO opts for PROLOR

Acquisition values PROLOR at $480 million

A partnership of VAST consequence

A partnership of VAST consequence

Proprietary chemistry platform will aid development of novel small molecules against multiple targets

Takeda acquires Inviragen for up to $250 million

Takeda acquires Inviragen for up to $250 million

Company gains promising vaccine candidates against dengue and hand, foot and mouth disease

Going small for broad potential

Going small for broad potential

Nimbus Discovery teams with Shire to co-develop therapies for rare diseases

Diagnostics

The blind men and the elephant

The blind men and the elephant

Progress in developing diagnostic tests hampered by differing perspectives of stakeholders involved

Go-with-the-flow cytometry

Go-with-the-flow cytometry

CytoVas allies with BD Biosciences to develop Vascular Health Profile

New hope for earlier autism diagnosis

New hope for earlier autism diagnosis

Largest prospective multisite autism clinical study offers promise of ASD diagnosis at 18 months

Integrating the clinical lab workflow

Integrating the clinical lab workflow

CollabRx and GeneInsight collaborate on interpretation and reporting service for clinical genetic sequencing

Omics & Systems Biology

Belfer Institute, Evotec forge oncology collaboration

Belfer Institute, Evotec forge oncology collaboration

The two parties aim to discover new oncology therapies targeting epigenetic mechanism

Giant leap into genomic medicine

Giant leap into genomic medicine

Jackson Laboratory, Connecticut hospitals explore new cancer therapies for children, adults

Laying a foundation for hematologic diagnostics

Laying a foundation for hematologic diagnostics

Foundation Medicine, MSKCC to co-develop product that will match patients with targeted therapies or clinical trials for hematologic malignancies

Making sense of mutations

Making sense of mutations

Collaboration seeks to understand genetic changes iPSCs acquire during differentiation
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