June 2009- Volume 5, Issue 6

In this Issue

Research & Development

Catalyst to ‘industrialize’ stem cell tech

Catalyst to ‘industrialize’ stem cell tech

Fate Therapeutics and Stemgent establish consortium to offer stem cell advances to the research market

Merck, Medarex and MBL enter antibody deal

Merck, Medarex and MBL enter antibody deal

Worldwide licensing agreement will target C. difficile infection

Companies to apply proprietary analytical technique to Alzheimer’s disease research

Companies to apply proprietary analytical technique to Alzheimer’s disease research

Back-scattering interferometry offers promise of revolutionizing screening for drugs that inhibit amyloid build-up

Utah researchers collaborate on stem cell therapy for ALS

Utah researchers collaborate on stem cell therapy for ALS

A team of Utah-based researchers are collaborating on a stem cell therapy to fight amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.

J&J pounces on Cougar

J&J pounces on Cougar

Johnson & Johnson to acquire oncology drug developer Cougar Biotechnology for $1 billion

Pfizer takes lead role in stem cell research

Pfizer takes lead role in stem cell research

Agreements with University College London, U of Wisconsin—Madison part of $100 million investment in international stem cell development program

Genomics & Proteomics

Twice is quite nice

Twice is quite nice

Isis and Alnylam extend their existing collaboration to develop single-stranded RNAi technology

Buying local

Buying local

TheraCode acquires fellow German company JPT Peptide Technologies

Researchers unlock autism puzzle piece

Researchers unlock autism puzzle piece

Largest study of autism finds genes linked to brain cell connections

That two may become one

That two may become one

MDS Pharma’s OncoPanel combined with Compendia’s Oncomine to help speed development of cancer drugs

Continuing down the right pathway

Continuing down the right pathway

Clinical Data continues to push FCGR work with monoclonal antibodies forward, adding two new research partners to explore this pathway

Serving it up rare

Serving it up rare

RainDance Technologies and Expression Analysis pair up on resequencing solutions looking at rare gene variants in cancer populations

Multiplex choice

Multiplex choice

Study probing how healthy younger adults make use of genetic tests

Automation & Instrumentation

Partners in pathway lucidation

Partners in pathway lucidation

Marketing agreement between Roche NimbleGen and Sigma-Aldrich seeks to ease epigenetic research bottlenecks

Responding to the market

Responding to the market

Cellectricon and BioFocus team up to advance high-throughput ion channel drug discovery

Bringing the biomarkers together

Bringing the biomarkers together

BD and Fujirebio Diagnostics to jointly develop biomarker assays for early ovarian cancer detection

Fighting the flu

Fighting the flu

Millipore and Microbix to co-develop novel purification process in influenza vaccine manufacturing

Breaking into the market

Breaking into the market

Co-marketing deal gives Agilent a good opening to enter the next-gen sequencing market and gives Illumina customers a new and necessary tool

PerkinElmer acquires Analytica of Branford

PerkinElmer acquires Analytica of Branford

Investment intended to enhance mass spec portfolio and expertise

Informatics

Taking a shine to Golden Helix

Taking a shine to Golden Helix

Agilent partners up with genetic analysis expert to create tool for wider-scale adoption of large CNV association studies

Heads in the clouds

Heads in the clouds

Applied Bio and Geospiza team up to offer next-gen genetic analysis via Amazon Web Services

Clinical trial traceability

Clinical trial traceability

Phase Forward acquires Waban Software to create integrated data analysis and reporting solution

Analyzing data at single-cell level

Analyzing data at single-cell level

PerkinElmer and Accelrys announce software collaboration to enable single-cell imaging using high-content screening technology

Dealing with a deluge of data

Dealing with a deluge of data

NextBio announces informatics licensing agreement with Merck

Global News

‘Made in China’ gains new meaning

‘Made in China’ gains new meaning

Abbott to select from 600 Chinese drug and biomarker compounds via HUYA Bioscience

Evotec catches Zebrafish

Evotec catches Zebrafish

Acquisition of Summit’s Zebrafish unit will expand geographic reach to Asia

South Pacific acquisition

South Pacific acquisition

Thermo Fisher Scientific pens $120M deal to acquire Biolab, a life science tools provider in New Zealand and Australia

Risks and rewards

Risks and rewards

AstraZeneca signs R&D deal worth up to $220 million with India’s Jubilant

Bayer, Ardea MEK-ing progress

Bayer, Ardea MEK-ing progress

Bayer and Ardea enter global agreement focused on the development of MEK inhibitors for the treatment of cancer

Commentary

How small CROs can survive and thrive in a shaky economy

How small CROs can survive and thrive in a shaky economy

In a shaky economy where demand from sponsor companies is slack, small CROs may want to consider various partnership strategies to improve stability and profitability—or be forced to liquidate. Examining current industry, economic and political trends will help CROs determine the best strategy and even thrive in the months ahead.

Patent News

ACLU mob attacks breast cancer test patent

ACLU mob attacks breast cancer test patent

The fight over the patentability of isolated genes is misplaced since patents are usually obtained not just for the isolated gene, but also for methods of use and as part of more complex assays or kits.

Editor's Focus

Media’s treatment of Big Pharma can sometimes be a bitter pill to swallow

Media’s treatment of Big Pharma can sometimes be a bitter pill to swallow

Last month, many major news groups elected to take what should have been perceived as good news in a bad economy, and presented it as yet another slam on greedy, bloodsucking Big Pharma. Is it any wonder that most Americans express dissatisfaction with our healthcare system?
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