July/August 2023- Volume 19, Issue 7

In this Issue

Editor's Focus

3D illustration close-up Intestinal villi.

Oral vaccines: from mouth to mucosal immunity

Oral vaccines: from mouth to mucosal immunity

Oral vaccines stop pathogens in their tracks before they get a chance to cause disease.
A newborn baby wearing a hat and swaddled in a blanket sleeps in a hospital bassinet.

Neonatal drug development comes out of the Dark Ages

Neonatal drug development comes out of the Dark Ages

Left out of clinical trials for years, preterm infants have very few drugs developed just for them. Regulators, industry, and neonatologists plan to fix that.
An image of a peanut against a blue background.

Next-generation peanut allergy therapies

Next-generation peanut allergy therapies

With childhood peanut allergies on the rise, scientists itch to find ways to prevent deadly reactions to this ubiquitous food.
An immunofluorescence microscope image of SARS-CoV-2 entering ciliated human nasal epithelial cells in an organoid.

Shadowing SARS-CoV-2 infections through mucus and cilia

Shadowing SARS-CoV-2 infections through mucus and cilia

Researchers discovered how SARS-CoV-2 invades and spreads through nasal epithelial cells, identifying potential new drug targets to prevent transmission.

Editors Insight

Glass bottles with a blue lid and label are lined up in a drug production factory.

What the mifepristone fight means for drug development

What the mifepristone fight means for drug development

A recent court case targeting the Food and Drug Administration’s regulatory authority sets a worrying precedent for the future of drug development.

Precision Medicine

Multiple 3D printers line a wall of a clean room.

A better way to build a breast

A better way to build a breast

As an alternative to reconstructive surgery, a degradable implant may offer a new way for the body to reconstruct a breast after mastectomy.
A black and white drawing of a human brain connected to an electrical cord.

Adaptive brain stimulation administers automated on-demand therapy

Adaptive brain stimulation administers automated on-demand therapy

A new form of brain stimulation treatment that responds to a patient’s brain activity could be life changing for people with neurological and psychiatric disorders.
A person’s hand holds up a 3D rendering of a brain with a glowing puzzle piece in the middle and a network of lines and dots, molecules, and drug capsules surrounding it.

Developing psychiatric drugs with precision focus

Developing psychiatric drugs with precision focus

Amit Etkin embraces the diverse underpinnings of depression and other psychiatric disorders and pairs patients with drugs based on their unique biology.

Infectious Disease

A row of seven tampons against a yellow background.

Managing menstrual toxic shock syndrome

Managing menstrual toxic shock syndrome

Menstrual toxic shock syndrome remains a life-threatening disease, so researchers are exploring safer tampon designs, toxin neutralization, and vaccination.

Diagnostics

A hand holds a smartphone displaying a rainbow screen.

Detecting disease with smartphone images

Detecting disease with smartphone images

To dismantle healthcare barriers in low-resource areas, researchers measure the color signatures of jaundice and anemia using a device that’s in everyone’s pocket.
Square wooden tiles are used to spell the word “fatigue”, with a hand putting the last letter into place.

Blood tests for chronic fatigue syndrome

Blood tests for chronic fatigue syndrome

People with myalgic encephalomyelitis/chronic fatigue syndrome can wait years for diagnoses; biomolecular tests are finally in development.
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